http://fieldresearch.msf.org/msf MSF captures, stores, indexes, preserves, and distributes digital research material. Search the Channel search http://fieldresearch.msf.org/msf/simple-search http://hdl.handle.net/10144/190431 Title: Knowledge, Attitude and Practice in the use of insecticide-treated mosquito nets distributed through antenatal and vaccination consultations in the "Cercle de Kangaba" region of Koulikoro, Mali<br/><br/>Authors: Oosterloo, Jan; Djoumessi, Jean Claude http://hdl.handle.net/10144/146531 Title: MSF ERB Members' CVs http://hdl.handle.net/10144/145257 Title: MSF UK Scientific Day Abstracts 2011<br/><br/>Authors: MSF UK http://hdl.handle.net/10144/142275 Title: Massive Increase, Spread, and Exchange of Extended Spectrum {beta}-Lactamase-Encoding Genes Among Intestinal Enterobacteriaceae in Hospitalized Children With Severe Acute Malnutrition in Niger.<br/><br/>Authors: Woerther, Paul-Louis; Angebault, Cécile; Jacquier, Hervé; Hugede, Henri-Charles; Janssens, Ann-Carole; Sayadi, Sani; El Mniai, Assiya; Armand-Lefèvre, Laurence; Ruppé, Etienne; Barbier, François; Raskine, Laurent; Page, Anne-Laure; de Rekeneire, Nathalie; Andremont, Antoine<br/><br/>Abstract: Background. From the time of CTX-M emergence, extended-spectrum β-lactamase-producing enterobacteria (ESBL-E) have spread worldwide in community settings as well as in hospitals, particularly in developing countries. Although their dissemination appears linked to Escherichia coli intestinal carriage, precise paths of this dynamic are largely unknown. Methods. Children from a pediatric renutrition center were prospectively enrolled in a fecal carriage study. Antibiotic exposure was recorded. ESBL-E strains were isolated using selective media from fecal samples obtained at admission and, when negative, also at discharge. ESBL-encoding genes were identified, their environments and plasmids were characterized, and clonality was assessed with polymerase chain reaction-based methods and pulsed-field gel electrophoresis for E. coli and Klebsiella pneumoniae. E. coli strains were subjected to multilocus sequence typing. Results. The ESBL-E carriage rate was 31% at admission in the 55 children enrolled. All children enrolled received antibiotics during hospitalization. Among the ESBL-E-negative children, 16 were resampled at discharge, and the acquisition rate was 94%. The bla(CTX-M-15) gene was found in >90% of the carriers. Genetic environments and plasmid characterization evidenced the roles of a worldwide, previously described, multidrug-resistant region and of IncF plasmids in CTX-M-15 E. coli dissemination. Diversity of CTX-M-15-carrying genetic structures and clonality of acquired ESBL E. coli suggested horizontal genetic transfer and underlined the potential of some ST types for nosocomial cross-transmission. Conclusions. Cross-transmission and high selective pressure lead to very high acquisition of ESBL-E carriage, contributing to dissemination in the community. Strict hygiene measures as well as careful balancing of benefit-risk ratio of current antibiotic policies need to be reevaluated. http://hdl.handle.net/10144/143511 Title: The published research paper: is it an important indicator of successful operational research at programme level?<br/><br/>Authors: Zachariah, R; Tayler-Smith, K.; Ngamvithayapong-Yanai, J.; Ota, M.; Murakami, K.; Ohkado, A.; Yamada, N.; Van Den Boogaard, W.; Draguez, B.; Ishikawa, N.; Harries, A. D. http://hdl.handle.net/10144/142315 Title: Burden of cervical abnormalities and cancer in a cohort of HIV-infected women in Mumbai, India<br/><br/>Authors: Isaakidis P; Pimple S; Varghese B; Da Silva E; Mansoor H; Ladomirska J; Sharma N; Caluwaerts S; Reid T<br/><br/>Description: ICAAP Poster 2011 http://hdl.handle.net/10144/197468 Title: OCG response to cholera in Haiti 2010-11<br/><br/>Authors: Bergeri, Isabel; Kampmueller, Sabine; Vienna Evaluation Unit http://hdl.handle.net/10144/142329 Title: Multidrug resistant TB treatment in HIV-infected patients: experience from a slum setting in Mumbai, India<br/><br/>Authors: Isaakidis P; Varghese B; Montaldo C; Da Silva E; Sotgui G; Migliori G; Pontalli E; Saranchuk P; Ladomirska J; Reid T<br/><br/>Description: ICAAP Poster 2011 http://hdl.handle.net/10144/143409 Title: Tracing patients lost to follow up in an urban slum: cooperation between a clinic and an NGO network in Mumbai, India<br/><br/>Authors: Errol L; Isaakidis P; Zachariah R; Eli M; Pilanka G; Maurya S; Geraets C; Ladomirska J; Patel S; Reid T<br/><br/>Description: ICAAP Conference 2011 http://hdl.handle.net/10144/142331 Title: Chronic Hepatitis B treatment outcomes in HIV co-infected patients in Mumbai, India<br/><br/>Authors: Isaakidis P; Mansoor H; Varghese B; Da Silva E; Deshpande A; Dal Molin T; Arnould L; Zachariah R; Reid T<br/><br/>Description: ICAAP Poster 2011