Marburg hemorrhagic fever in Durba and Watsa, Democratic Republic of the Congo: clinical documentation, features of illness, and treatment

Hdl Handle:
http://hdl.handle.net/10144/116349
Title:
Marburg hemorrhagic fever in Durba and Watsa, Democratic Republic of the Congo: clinical documentation, features of illness, and treatment
Authors:
Colebunders, Robert; Tshomba, Antoine; Van Kerkhove, Maria D; Bausch, Daniel G; Campbell, Pat; Libande, Modeste; Pirard, Patricia; Tshioko, Florimond; Mardel, Simon; Mulangu, Sabue; Sleurs, Hilde; Rollin, Pierre E; Muyembe-Tamfum, Jean-Jacques; Jeffs, Benjamin; Borchert, Matthias
Journal:
The Journal of Infectious Diseases
Abstract:
The objective of the present study was to describe day of onset and duration of symptoms of Marburg hemorrhagic fever (MHF), to summarize the treatments applied, and to assess the quality of clinical documentation. Surveillance and clinical records of 77 patients with MHF cases were reviewed. Initial symptoms included fever, headache, general pain, nausea, vomiting, and anorexia (median day of onset, day 1-2), followed by hemorrhagic manifestations (day 5-8+), and terminal symptoms included confusion, agitation, coma, anuria, and shock. Treatment in isolation wards was acceptable, but the quality of clinical documentation was unsatisfactory. Improved clinical documentation is necessary for a basic evaluation of supportive treatment.
Affiliation:
Institute of Tropical Medicine Antwerp, Antwerp, Belgium; University of Antwerp, Antwerp, Belgium; Medecins Sans Frontieres, Brussels, Belgium; Okimo Hospital, Watsa, Democratic Republic of the Congo; Ministry of Health, Kinshasa, Democratic Republic of the Congo; World Health Organization, Kinshasa, Democratic Republic of the Congo; Institut National de Recherche Biomedicale, Kinshasa, Democratic Republic of the Congo; London School of Hygiene and Tropical Medicine, London, United Kingdom; Centers for Disease Control and Prevention, Atlanta, Georgia; Tulane School of Public Health and Tropical Medicine, New Orleans, Louisiana; Medecins Sans Frontieres, Amsterdam, The Netherlands; World Health Organization, Geneva, Switzerland
Issue Date:
15-Nov-2007
URI:
http://hdl.handle.net/10144/116349
DOI:
10.1086/520543
PubMed ID:
17940943
Additional Links:
http://www.journals.uchicago.edu/doi/abs/10.1086/520543?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
Type:
Article
Language:
en
ISSN:
0022-1899
Appears in Collections:
Other Diseases

Full metadata record

DC FieldValue Language
dc.contributor.authorColebunders, Roberten
dc.contributor.authorTshomba, Antoineen
dc.contributor.authorVan Kerkhove, Maria Den
dc.contributor.authorBausch, Daniel Gen
dc.contributor.authorCampbell, Paten
dc.contributor.authorLibande, Modesteen
dc.contributor.authorPirard, Patriciaen
dc.contributor.authorTshioko, Florimonden
dc.contributor.authorMardel, Simonen
dc.contributor.authorMulangu, Sabueen
dc.contributor.authorSleurs, Hildeen
dc.contributor.authorRollin, Pierre Een
dc.contributor.authorMuyembe-Tamfum, Jean-Jacquesen
dc.contributor.authorJeffs, Benjaminen
dc.contributor.authorBorchert, Matthiasen
dc.date.accessioned2010-11-25T16:38:52Z-
dc.date.available2010-11-25T16:38:52Z-
dc.date.issued2007-11-15-
dc.identifier.citationJ. Infect. Dis. 2007;196 Suppl 2:S148-53en
dc.identifier.issn0022-1899-
dc.identifier.pmid17940943-
dc.identifier.doi10.1086/520543-
dc.identifier.urihttp://hdl.handle.net/10144/116349-
dc.description.abstractThe objective of the present study was to describe day of onset and duration of symptoms of Marburg hemorrhagic fever (MHF), to summarize the treatments applied, and to assess the quality of clinical documentation. Surveillance and clinical records of 77 patients with MHF cases were reviewed. Initial symptoms included fever, headache, general pain, nausea, vomiting, and anorexia (median day of onset, day 1-2), followed by hemorrhagic manifestations (day 5-8+), and terminal symptoms included confusion, agitation, coma, anuria, and shock. Treatment in isolation wards was acceptable, but the quality of clinical documentation was unsatisfactory. Improved clinical documentation is necessary for a basic evaluation of supportive treatment.en
dc.language.isoenen
dc.relation.urlhttp://www.journals.uchicago.edu/doi/abs/10.1086/520543?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmeden
dc.rightsPublished by Infectious Diseases Society of America Archived on this site with permission and copyright 2007 by the Infectious Diseases Society of America, [url]http://www.journals.uchicago.edu/toc/jid[/url]en
dc.subject.meshAnimalsen
dc.subject.meshDemocratic Republic of the Congoen
dc.subject.meshDisease Progressionen
dc.subject.meshDocumentationen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshMaleen
dc.subject.meshMarburg Virus Diseaseen
dc.subject.meshMarburgvirusen
dc.subject.meshMedical Recordsen
dc.subject.meshRetrospective Studiesen
dc.subject.meshSurvival Rateen
dc.titleMarburg hemorrhagic fever in Durba and Watsa, Democratic Republic of the Congo: clinical documentation, features of illness, and treatmenten
dc.typeArticleen
dc.contributor.departmentInstitute of Tropical Medicine Antwerp, Antwerp, Belgium; University of Antwerp, Antwerp, Belgium; Medecins Sans Frontieres, Brussels, Belgium; Okimo Hospital, Watsa, Democratic Republic of the Congo; Ministry of Health, Kinshasa, Democratic Republic of the Congo; World Health Organization, Kinshasa, Democratic Republic of the Congo; Institut National de Recherche Biomedicale, Kinshasa, Democratic Republic of the Congo; London School of Hygiene and Tropical Medicine, London, United Kingdom; Centers for Disease Control and Prevention, Atlanta, Georgia; Tulane School of Public Health and Tropical Medicine, New Orleans, Louisiana; Medecins Sans Frontieres, Amsterdam, The Netherlands; World Health Organization, Geneva, Switzerlanden
dc.identifier.journalThe Journal of Infectious Diseasesen

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