Assessment of Dietary Exposure to Some Persistent Organic Pollutants in the Republic of Karakalpakstan of Uzbekistan.

Hdl Handle:
http://hdl.handle.net/10144/16897
Title:
Assessment of Dietary Exposure to Some Persistent Organic Pollutants in the Republic of Karakalpakstan of Uzbekistan.
Authors:
Muntean, N; Jermini, M; Small, I; Falzon, D; Fürst, P; Migliorati, G; Scortichini, G; Forti, A F; Anklam, E; von Holst, C; Niyazmatov, B; Bahkridinov, S; Aertgeerts, R; Bertollini, R; Tirado, C; Kolb, A
Journal:
Environmental Health Perspectives
Abstract:
A 1999 study heightened long-standing concerns over persistent organic pollutant contamination in the Aral Sea area, detecting elevated levels in breast milk and cord blood of women in Karakalpakstan (western Uzbekistan). These findings prompted a collaborative research study aimed at linking such human findings with evidence of food chain contamination in the area. An international team carried out analyses of organochlorine and organophosphate pesticides, polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins (PCDDs), and polychlorinated dibenzofurans (PCDFs) on samples of 12 foods commonly produced and consumed in Karakalpakstan. Analysis consistently detected long-lasting organochlorine pesticides and their metabolites in all foods of animal origin and in some vegetables such as onions and carrots--two low-cost components of many traditional dishes. Levels of PCBs were relatively low in all samples except fish. Analyses revealed high levels of PCDDs and PCDFs (together often termed "dioxins") in sheep fat, dairy cream, eggs, and edible cottonseed oil, among other foodstuffs. These findings indicate that food traditionally grown, sold, and consumed in Karakalpakstan is a major route of human exposure to several persistent toxic contaminants, including the most toxic of dioxins, 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD). Intake estimations demonstrate that consumption of even small amounts of locally grown food may expose consumers to dioxin levels that considerably exceed the monthly tolerable dioxin intake levels set by the World Health Organization. Data presented in this study allow a first assessment of the risk associated with the consumption of certain food products in Karakalpakstan and highlight a critical public health situation.
Affiliation:
Médecins sans Frontières--Holland, Tashkent, Uzbekistan.
Publisher:
Published by National Institute of Environmental Health Sciences
Issue Date:
Aug-2003
URI:
http://hdl.handle.net/10144/16897
PubMed ID:
12896851
Language:
en
ISSN:
0091-6765
Appears in Collections:
Nutrition

Full metadata record

DC FieldValue Language
dc.contributor.authorMuntean, N-
dc.contributor.authorJermini, M-
dc.contributor.authorSmall, I-
dc.contributor.authorFalzon, D-
dc.contributor.authorFürst, P-
dc.contributor.authorMigliorati, G-
dc.contributor.authorScortichini, G-
dc.contributor.authorForti, A F-
dc.contributor.authorAnklam, E-
dc.contributor.authorvon Holst, C-
dc.contributor.authorNiyazmatov, B-
dc.contributor.authorBahkridinov, S-
dc.contributor.authorAertgeerts, R-
dc.contributor.authorBertollini, R-
dc.contributor.authorTirado, C-
dc.contributor.authorKolb, A-
dc.date.accessioned2008-01-25T15:49:23Z-
dc.date.available2008-01-25T15:49:23Z-
dc.date.issued2003-08-
dc.identifier.citationAssessment of Dietary Exposure to Some Persistent Organic Pollutants in the Republic of Karakalpakstan of Uzbekistan. 2003, 111 (10):1306-11 Environ. Health Perspect.en
dc.identifier.issn0091-6765-
dc.identifier.pmid12896851-
dc.identifier.urihttp://hdl.handle.net/10144/16897-
dc.description.abstractA 1999 study heightened long-standing concerns over persistent organic pollutant contamination in the Aral Sea area, detecting elevated levels in breast milk and cord blood of women in Karakalpakstan (western Uzbekistan). These findings prompted a collaborative research study aimed at linking such human findings with evidence of food chain contamination in the area. An international team carried out analyses of organochlorine and organophosphate pesticides, polychlorinated biphenyls (PCBs), polychlorinated dibenzo-p-dioxins (PCDDs), and polychlorinated dibenzofurans (PCDFs) on samples of 12 foods commonly produced and consumed in Karakalpakstan. Analysis consistently detected long-lasting organochlorine pesticides and their metabolites in all foods of animal origin and in some vegetables such as onions and carrots--two low-cost components of many traditional dishes. Levels of PCBs were relatively low in all samples except fish. Analyses revealed high levels of PCDDs and PCDFs (together often termed "dioxins") in sheep fat, dairy cream, eggs, and edible cottonseed oil, among other foodstuffs. These findings indicate that food traditionally grown, sold, and consumed in Karakalpakstan is a major route of human exposure to several persistent toxic contaminants, including the most toxic of dioxins, 2,3,7,8-tetrachlorodibenzo-p-dioxin (2,3,7,8-TCDD). Intake estimations demonstrate that consumption of even small amounts of locally grown food may expose consumers to dioxin levels that considerably exceed the monthly tolerable dioxin intake levels set by the World Health Organization. Data presented in this study allow a first assessment of the risk associated with the consumption of certain food products in Karakalpakstan and highlight a critical public health situation.en
dc.language.isoenen
dc.publisherPublished by National Institute of Environmental Health Sciences-
dc.rightsArchived on this site by Open Access permissionen
dc.subject.meshDioxinsen
dc.subject.meshEnvironmental Pollutantsen
dc.subject.meshFemaleen
dc.subject.meshFood Contaminationen
dc.subject.meshHumansen
dc.subject.meshInsecticidesen
dc.subject.meshMeat Productsen
dc.subject.meshMilk, Humanen
dc.subject.meshOrganic Chemicalsen
dc.subject.meshOrganophosphorus Compoundsen
dc.subject.meshPlants, Edibleen
dc.subject.meshUzbekistanen
dc.titleAssessment of Dietary Exposure to Some Persistent Organic Pollutants in the Republic of Karakalpakstan of Uzbekistan.en
dc.contributor.departmentMédecins sans Frontières--Holland, Tashkent, Uzbekistan.en
dc.identifier.journalEnvironmental Health Perspectivesen

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