HIV Viral Load Monitoring in Resource-Limited Regions: Optional or Necessary?

Hdl Handle:
http://hdl.handle.net/10144/17733
Title:
HIV Viral Load Monitoring in Resource-Limited Regions: Optional or Necessary?
Authors:
Calmy, A; Ford, N; Hirschel, B; Reynolds, S; Lynen, L; Goemaere, E; Garcia de la Vega, F; Perrin, L; Rodriguez, W
Journal:
Clinical Infectious Diseases
Abstract:
Although it is a standard practice in high-income countries, determination of the human immunodeficiency virus (HIV) load is not recommended in developing countries because of the costs and technical constraints. As more and more countries establish capacity to provide second-line therapy, and as costs and technological constraints associated with viral load testing decrease, the question of whether determination of the viral load is necessary deserves attention. Viral load testing could increase in importance as a guide for clinical decisions on when to switch to second-line treatment and on how to optimize the duration of the first-line treatment regimen. In addition, the viral load is a particularly useful tool for monitoring adherence to treatment, performing sentinel surveillance, and diagnosing HIV infection in children aged <18 months. Rather than considering viral load data to be an unaffordable luxury, efforts should be made to ensure that viral load testing becomes affordable, simple, and easy to use in resource-limited settings.
Affiliation:
Medecins sans Frontieres, Access to Medicines Campaign, Geneva, 1211, Switzerland. acalmy@gmail.com
Publisher:
Published by: Infectious Diseases Society of America
Issue Date:
1-Jan-2007
URI:
http://hdl.handle.net/10144/17733
DOI:
10.1086/510073
PubMed ID:
17143828
Additional Links:
http://www.journals.uchicago.edu/page/cid/brief.html
Language:
en
ISSN:
1537-6591
Appears in Collections:
HIV/AIDS

Full metadata record

DC FieldValue Language
dc.contributor.authorCalmy, A-
dc.contributor.authorFord, N-
dc.contributor.authorHirschel, B-
dc.contributor.authorReynolds, S-
dc.contributor.authorLynen, L-
dc.contributor.authorGoemaere, E-
dc.contributor.authorGarcia de la Vega, F-
dc.contributor.authorPerrin, L-
dc.contributor.authorRodriguez, W-
dc.date.accessioned2008-02-07T16:10:49Z-
dc.date.available2008-02-07T16:10:49Z-
dc.date.issued2007-01-01-
dc.identifier.citationHIV Viral Load Monitoring in Resource-Limited Regions: Optional or Necessary? 2007, 44 (1):128-34 Clin. Infect. Dis.en
dc.identifier.issn1537-6591-
dc.identifier.pmid17143828-
dc.identifier.doi10.1086/510073-
dc.identifier.urihttp://hdl.handle.net/10144/17733-
dc.description.abstractAlthough it is a standard practice in high-income countries, determination of the human immunodeficiency virus (HIV) load is not recommended in developing countries because of the costs and technical constraints. As more and more countries establish capacity to provide second-line therapy, and as costs and technological constraints associated with viral load testing decrease, the question of whether determination of the viral load is necessary deserves attention. Viral load testing could increase in importance as a guide for clinical decisions on when to switch to second-line treatment and on how to optimize the duration of the first-line treatment regimen. In addition, the viral load is a particularly useful tool for monitoring adherence to treatment, performing sentinel surveillance, and diagnosing HIV infection in children aged <18 months. Rather than considering viral load data to be an unaffordable luxury, efforts should be made to ensure that viral load testing becomes affordable, simple, and easy to use in resource-limited settings.en
dc.language.isoenen
dc.publisherPublished by: Infectious Diseases Society of America-
dc.relation.urlhttp://www.journals.uchicago.edu/page/cid/brief.html-
dc.rightsArchived on this site with permission and copyright by the Infectious Diseases Society of Americaen
dc.subject.meshAnti-HIV Agentsen
dc.subject.meshDeveloping Countriesen
dc.subject.meshHIV Infectionsen
dc.subject.meshHIV-1en
dc.subject.meshHumansen
dc.subject.meshInfanten
dc.subject.meshInfant, Newbornen
dc.subject.meshPatient Complianceen
dc.subject.meshTreatment Failureen
dc.subject.meshTreatment Outcomeen
dc.subject.meshViral Loaden
dc.titleHIV Viral Load Monitoring in Resource-Limited Regions: Optional or Necessary?en
dc.contributor.departmentMedecins sans Frontieres, Access to Medicines Campaign, Geneva, 1211, Switzerland. acalmy@gmail.comen
dc.identifier.journalClinical Infectious Diseasesen

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