Visceral Leishmaniasis in Southern Sudan: Status of Healthy Villagers in Epidemic Conditions.

Hdl Handle:
http://hdl.handle.net/10144/18279
Title:
Visceral Leishmaniasis in Southern Sudan: Status of Healthy Villagers in Epidemic Conditions.
Authors:
Seaman, J; Ashford, R W; Schorscher, J; Dereure, J
Journal:
Annals of Tropical Medicine and Parasitology
Abstract:
A combination of interview, serology and skin testing was used to investigate the status of apparently healthy villagers during a visceral leishmaniasis epidemic in southern Sudan. The number of people who had died equalled the number who were alive at the time of the survey. The direct agglutination test (DAT) identified 10% of the people as being serologically positive. Most young children (36/39) and 34% (22/64) of adults had neither positive serology nor skin test. About 64% (42/66) of adults had positive skin tests. In two villages, 54% and 76% of those over four years of age showed evidence of having been infected. The mortality associated with infection was estimated as at least 69%; 25% of those infected appeared to have cured spontaneously. The outcome for the remaining 6% was still doubtful. Even in this devastating epidemic there is, therefore, evidence of a considerable amount of infection without severe disease. Serological tests, while useful clinically, are apparently not useful for detecting early cases. Combined skin testing and serology produces a comprehensive though partially hypothetical picture.
Affiliation:
MSF Holland (Artsen Zonder Grenzen), Nairobi, Kenya.
Publisher:
Published by: Maney Publishing
Issue Date:
Oct-1992
URI:
http://hdl.handle.net/10144/18279
PubMed ID:
1288429
Additional Links:
http://www.maney.co.uk/journals/atmp
Language:
en
ISSN:
0003-4983
Appears in Collections:
Leishmaniasis/Kala Azar

Full metadata record

DC FieldValue Language
dc.contributor.authorSeaman, J-
dc.contributor.authorAshford, R W-
dc.contributor.authorSchorscher, J-
dc.contributor.authorDereure, J-
dc.date.accessioned2008-02-14T11:42:44Z-
dc.date.available2008-02-14T11:42:44Z-
dc.date.issued1992-10-
dc.identifier.citationVisceral Leishmaniasis in Southern Sudan: Status of Healthy Villagers in Epidemic Conditions. 1992, 86 (5):481-6 Ann. Trop. Med. Parasitol.en
dc.identifier.issn0003-4983-
dc.identifier.pmid1288429-
dc.identifier.urihttp://hdl.handle.net/10144/18279-
dc.description.abstractA combination of interview, serology and skin testing was used to investigate the status of apparently healthy villagers during a visceral leishmaniasis epidemic in southern Sudan. The number of people who had died equalled the number who were alive at the time of the survey. The direct agglutination test (DAT) identified 10% of the people as being serologically positive. Most young children (36/39) and 34% (22/64) of adults had neither positive serology nor skin test. About 64% (42/66) of adults had positive skin tests. In two villages, 54% and 76% of those over four years of age showed evidence of having been infected. The mortality associated with infection was estimated as at least 69%; 25% of those infected appeared to have cured spontaneously. The outcome for the remaining 6% was still doubtful. Even in this devastating epidemic there is, therefore, evidence of a considerable amount of infection without severe disease. Serological tests, while useful clinically, are apparently not useful for detecting early cases. Combined skin testing and serology produces a comprehensive though partially hypothetical picture.en
dc.language.isoenen
dc.publisherPublished by: Maney Publishing-
dc.relation.urlhttp://www.maney.co.uk/journals/atmp-
dc.rightsArchived on this site with the kind permission of Maney Publishingen
dc.subject.meshAdolescenten
dc.subject.meshAdulten
dc.subject.meshAge Factorsen
dc.subject.meshAgglutination Testsen
dc.subject.meshChilden
dc.subject.meshChild, Preschoolen
dc.subject.meshDisease Outbreaksen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshInfanten
dc.subject.meshLeishmaniasis, Visceralen
dc.subject.meshMaleen
dc.subject.meshRural Populationen
dc.subject.meshSex Factorsen
dc.subject.meshSkin Testsen
dc.subject.meshSudanen
dc.titleVisceral Leishmaniasis in Southern Sudan: Status of Healthy Villagers in Epidemic Conditions.en
dc.contributor.departmentMSF Holland (Artsen Zonder Grenzen), Nairobi, Kenya.en
dc.identifier.journalAnnals of Tropical Medicine and Parasitologyen

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