In vitro susceptibility of 120 strains of Neisseria gonorrhoeae isolated in Kyrghyzstan.

Hdl Handle:
http://hdl.handle.net/10144/18353
Title:
In vitro susceptibility of 120 strains of Neisseria gonorrhoeae isolated in Kyrghyzstan.
Authors:
Dorlencourt, F; Boireaux, C; Sednaoui, P; Danilenko, N V; Legros, D
Journal:
Sexually Transmitted Diseases
Abstract:
BACKGROUND: The World Health Organization has established a worldwide program for gonococcal antimicrobial surveillance, but so far no data on gonococcal susceptibility in Central Asia are available. GOAL: The need for biological data on the susceptibility of Neisseria gonorrhoeae in Kyrghyzstan, to enable adaptation of the national treatment protocol for gonococcal infections, led Médecins Sans Frontières and Epicentre to conduct a survey in collaboration with the Alfred Fournier Institute in Paris and the health authorities in Bishkek. STUDY DESIGN: In vitro susceptibility of N gonorrhoeae strains was determined with use of the reference agar-plate dilution technique. RESULTS: Results for 11 antibiotics tested on 120 strains of gonococci showed a low proportion (11.7%) of penicillinase-producing N gonorrhoeae and high proportions of intermediate or resistant strains to the majority of the antibiotics tested, including fluoroquinolones (>or=25% of strains resistant). All the strains were susceptible to spectinomycin, and only two strains had decreased susceptibility to cefixime. CONCLUSION: The therapeutic choices available in Kyrghyzstan appear to be limited to cephalosporins and spectinomycin.
Affiliation:
Epicentre, Paris.
Issue Date:
Jul-2002
URI:
http://hdl.handle.net/10144/18353
PubMed ID:
12170124
Language:
en
ISSN:
0148-5717
Appears in Collections:
Other Diseases

Full metadata record

DC FieldValue Language
dc.contributor.authorDorlencourt, F-
dc.contributor.authorBoireaux, C-
dc.contributor.authorSednaoui, P-
dc.contributor.authorDanilenko, N V-
dc.contributor.authorLegros, D-
dc.date.accessioned2008-02-14T15:52:05Z-
dc.date.available2008-02-14T15:52:05Z-
dc.date.issued2002-07-
dc.identifier.citationIn vitro susceptibility of 120 strains of Neisseria gonorrhoeae isolated in Kyrghyzstan. 2002, 29 (7):376-8notSex Transm Disen
dc.identifier.issn0148-5717-
dc.identifier.pmid12170124-
dc.identifier.urihttp://hdl.handle.net/10144/18353-
dc.description.abstractBACKGROUND: The World Health Organization has established a worldwide program for gonococcal antimicrobial surveillance, but so far no data on gonococcal susceptibility in Central Asia are available. GOAL: The need for biological data on the susceptibility of Neisseria gonorrhoeae in Kyrghyzstan, to enable adaptation of the national treatment protocol for gonococcal infections, led Médecins Sans Frontières and Epicentre to conduct a survey in collaboration with the Alfred Fournier Institute in Paris and the health authorities in Bishkek. STUDY DESIGN: In vitro susceptibility of N gonorrhoeae strains was determined with use of the reference agar-plate dilution technique. RESULTS: Results for 11 antibiotics tested on 120 strains of gonococci showed a low proportion (11.7%) of penicillinase-producing N gonorrhoeae and high proportions of intermediate or resistant strains to the majority of the antibiotics tested, including fluoroquinolones (>or=25% of strains resistant). All the strains were susceptible to spectinomycin, and only two strains had decreased susceptibility to cefixime. CONCLUSION: The therapeutic choices available in Kyrghyzstan appear to be limited to cephalosporins and spectinomycin.en
dc.language.isoenen
dc.rightsPublished by Wolters Kluwer Lippincott Williams & Wilkins - Archived on this site by kind permission Wolters Kluweren
dc.subject.meshAnti-Bacterial Agentsen
dc.subject.meshAsia, Centralen
dc.subject.meshDrug Resistance, Bacterialen
dc.subject.meshGonorrheaen
dc.subject.meshHumansen
dc.subject.meshMaleen
dc.subject.meshMicrobial Sensitivity Testsen
dc.subject.meshNeisseria gonorrhoeaeen
dc.titleIn vitro susceptibility of 120 strains of Neisseria gonorrhoeae isolated in Kyrghyzstan.en
dc.contributor.departmentEpicentre, Paris.en
dc.identifier.journalSexually Transmitted Diseasesen

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