Loss to follow up from isoniazid preventive therapy among adults attending HIV voluntary counseling and testing sites in Uganda.

Hdl Handle:
http://hdl.handle.net/10144/204848
Title:
Loss to follow up from isoniazid preventive therapy among adults attending HIV voluntary counseling and testing sites in Uganda.
Authors:
Namuwenge, P M; Mukonzo, J K; Kiwanuka, N; Wanyenze, R; Byaruhanga, R; Bissell, K; Zachariah, R
Journal:
Transactions of the Royal Society of Tropical Medicine and Hygiene
Abstract:
Among HIV-infected adults attending non-governmental organization voluntary counseling and testing (VCT) sites in Uganda that provide a nine-month course of isoniazid preventive treatment (IPT), we report on loss to follow-up (LTFU) and its associated risk factors. The design was a retrospective cohort study of program data spanning a three year period (2006-2008). A total of 586 IPT patients were enrolled of whom 335 (57.1%) were females with a mean age of 34 years. Of those starting IPT, 341 (58.1%) were lost to follow-up, 197 (33.6%) completed IPT, 29 (4.9%) were discontinued and 19 (3.2%) died. The return rates at one, three, five and seven months were 78.0% (457), 62.1% (364), 52.9% (310) and 33.6% (197) respectively. Being less than 30 years of age, widowed, separated, or divorced were found to be associated with a higher risk of loss to follow-up. Sudden improvement in retention on IPT was observed between the years 2006 and 2007, although causes of the improvement are poorly understood hence the need for more research. At non-governmental VCT sites in Uganda, six out of ten individuals enrolled on IPT are lost to follow-up and efforts to reduce this attrition including systems strengthening might play a critical role in the success of IPT programs.
Affiliation:
Makerere University School of Public Health P.O. Box 7072 Kampala Uganda; AIDS Information Centre headquarters, P.O. Box 10446 Kampala, Uganda.
Issue Date:
Feb-2012
URI:
http://hdl.handle.net/10144/204848
DOI:
10.1016/j.trstmh.2011.10.015
PubMed ID:
22154974
Language:
en
ISSN:
1878-3503
Appears in Collections:
HIV/AIDS

Full metadata record

DC FieldValue Language
dc.contributor.authorNamuwenge, P Men
dc.contributor.authorMukonzo, J Ken
dc.contributor.authorKiwanuka, Nen
dc.contributor.authorWanyenze, Ren
dc.contributor.authorByaruhanga, Ren
dc.contributor.authorBissell, Ken
dc.contributor.authorZachariah, Ren
dc.date.accessioned2012-01-25T19:44:41Z-
dc.date.available2012-01-25T19:44:41Z-
dc.date.issued2012-02-
dc.identifier.citationLoss to follow up from isoniazid preventive therapy among adults attending HIV voluntary counseling and testing sites in Uganda. 2012, 106 (2):84-9 Trans. R. Soc. Trop. Med. Hyg.en
dc.identifier.issn1878-3503-
dc.identifier.pmid22154974-
dc.identifier.doi10.1016/j.trstmh.2011.10.015-
dc.identifier.urihttp://hdl.handle.net/10144/204848-
dc.description.abstractAmong HIV-infected adults attending non-governmental organization voluntary counseling and testing (VCT) sites in Uganda that provide a nine-month course of isoniazid preventive treatment (IPT), we report on loss to follow-up (LTFU) and its associated risk factors. The design was a retrospective cohort study of program data spanning a three year period (2006-2008). A total of 586 IPT patients were enrolled of whom 335 (57.1%) were females with a mean age of 34 years. Of those starting IPT, 341 (58.1%) were lost to follow-up, 197 (33.6%) completed IPT, 29 (4.9%) were discontinued and 19 (3.2%) died. The return rates at one, three, five and seven months were 78.0% (457), 62.1% (364), 52.9% (310) and 33.6% (197) respectively. Being less than 30 years of age, widowed, separated, or divorced were found to be associated with a higher risk of loss to follow-up. Sudden improvement in retention on IPT was observed between the years 2006 and 2007, although causes of the improvement are poorly understood hence the need for more research. At non-governmental VCT sites in Uganda, six out of ten individuals enrolled on IPT are lost to follow-up and efforts to reduce this attrition including systems strengthening might play a critical role in the success of IPT programs.en
dc.language.isoenen
dc.rightsPublished by Elsevier Archived on this site with the kind permission of Elsevier Ltd. ([url]http://www.sciencedirect.com/science/journal/00359203[/url]) and the Royal Society of Tropical Medicine and Hygiene ([url]http://www.rstmh.org/transactions.asp[/url])en
dc.titleLoss to follow up from isoniazid preventive therapy among adults attending HIV voluntary counseling and testing sites in Uganda.en
dc.contributor.departmentMakerere University School of Public Health P.O. Box 7072 Kampala Uganda; AIDS Information Centre headquarters, P.O. Box 10446 Kampala, Uganda.en
dc.identifier.journalTransactions of the Royal Society of Tropical Medicine and Hygieneen

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