Outcomes of patients with Kaposi's sarcoma who start antiretroviral therapy under routine programme conditions in Malawi.

Hdl Handle:
http://hdl.handle.net/10144/22937
Title:
Outcomes of patients with Kaposi's sarcoma who start antiretroviral therapy under routine programme conditions in Malawi.
Authors:
Makombe, S D; Harries, A D; Yu, J K L; Hochgesang, M; Mhango, E; Weigel, R; Pasulani, O; Fitzgerald, M; Schouten, E J; Libamba, E
Journal:
Tropical Doctor
Abstract:
AIDS-associated Kaposi's sarcoma (KS) is the most common AIDS-related malignancy in sub-Saharan Africa, with a generally unfavourable prognosis. We report on six-month and 12-month cohort treatment outcomes of human immunodeficiency virus (HIV)-positive KS patients and HIV-positive non-KS patients treated with antiretroviral therapy (ART) in public sector facilities in Malawi. Data were collected from standardized antiretroviral (ARV) patient master cards and ARV patient registers. Between July and September 2005, 7905 patients started ART-488 (6%) with a diagnosis of KS and 7417 with a non-KS diagnosis. Between January and March 2005, 4580 patients started ART-326 (7%) with a diagnosis of KS and 4254 with a non-KS diagnosis. At six-months and 12-months, significantly fewer KS patients were alive and significantly more had died or defaulted compared to non-KS patients. HIV-positive KS patients on ART in Malawi have worse outcomes than other patients on ART. Methods designed to improve these outcomes must be found.
Affiliation:
Clinical HIV Unit, Ministry of Health, PO Box 30377, Lilongwe, Malawi.
Publisher:
Royal Society of Medicine
Issue Date:
Jan-2008
URI:
http://hdl.handle.net/10144/22937
DOI:
10.1258/td.2007.060023
PubMed ID:
18302849
Additional Links:
http://td.rsmjournals.com
Language:
en
ISSN:
0049-4755
Appears in Collections:
HIV/AIDS

Full metadata record

DC FieldValue Language
dc.contributor.authorMakombe, S D-
dc.contributor.authorHarries, A D-
dc.contributor.authorYu, J K L-
dc.contributor.authorHochgesang, M-
dc.contributor.authorMhango, E-
dc.contributor.authorWeigel, R-
dc.contributor.authorPasulani, O-
dc.contributor.authorFitzgerald, M-
dc.contributor.authorSchouten, E J-
dc.contributor.authorLibamba, E-
dc.date.accessioned2008-04-10T15:55:20Z-
dc.date.available2008-04-10T15:55:20Z-
dc.date.issued2008-01-
dc.identifier.citationOutcomes of patients with Kaposi's sarcoma who start antiretroviral therapy under routine programme conditions in Malawi. 2008, 38 (1):5-7notTrop Docten
dc.identifier.issn0049-4755-
dc.identifier.pmid18302849-
dc.identifier.doi10.1258/td.2007.060023-
dc.identifier.urihttp://hdl.handle.net/10144/22937-
dc.description.abstractAIDS-associated Kaposi's sarcoma (KS) is the most common AIDS-related malignancy in sub-Saharan Africa, with a generally unfavourable prognosis. We report on six-month and 12-month cohort treatment outcomes of human immunodeficiency virus (HIV)-positive KS patients and HIV-positive non-KS patients treated with antiretroviral therapy (ART) in public sector facilities in Malawi. Data were collected from standardized antiretroviral (ARV) patient master cards and ARV patient registers. Between July and September 2005, 7905 patients started ART-488 (6%) with a diagnosis of KS and 7417 with a non-KS diagnosis. Between January and March 2005, 4580 patients started ART-326 (7%) with a diagnosis of KS and 4254 with a non-KS diagnosis. At six-months and 12-months, significantly fewer KS patients were alive and significantly more had died or defaulted compared to non-KS patients. HIV-positive KS patients on ART in Malawi have worse outcomes than other patients on ART. Methods designed to improve these outcomes must be found.en
dc.language.isoenen
dc.publisherRoyal Society of Medicineen
dc.relation.urlhttp://td.rsmjournals.comen
dc.rightsReproduced on this site with the permission of Royal Society of Medicine Press, London ([url]http://www.rsmpress.co.uk/td.htm[/url])en
dc.titleOutcomes of patients with Kaposi's sarcoma who start antiretroviral therapy under routine programme conditions in Malawi.en
dc.contributor.departmentClinical HIV Unit, Ministry of Health, PO Box 30377, Lilongwe, Malawi.en
dc.identifier.journalTropical Doctoren

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