Antibiotic Sensitivity of Endemic Shigella in Mbarara, Uganda.

Hdl Handle:
http://hdl.handle.net/10144/23165
Title:
Antibiotic Sensitivity of Endemic Shigella in Mbarara, Uganda.
Authors:
Legros, D; Ochola, D; Lwanga, N; Guma, G
Journal:
East African Medical Journal
Abstract:
We analysed the chimio-sensitivity to antibiotics of endemic strains of Shigella isolated in Mbarara district, southwest Uganda. Twenty four strains were isolated, of which none was sensitive to cotrimoxazole and eight (33.4%, 95% CI [15.6-55.3]) to ampicillin, the two antibiotics recommended to treat dysentery during non epidemic periods in Uganda. Two isolates were resistant to nalidixic acid and none was resistant to the fluoroquinolones (Ciprofloxacin, Norfloxacin). It is concluded that the results of this survey could be used to facilitate the elaboration of a new treatment protocol to treat endemic dysentery cases in Uganda.
Affiliation:
Epicentre, Kampala, Uganda.
Issue Date:
Mar-1998
URI:
http://hdl.handle.net/10144/23165
PubMed ID:
9640814
Language:
en
ISSN:
0012-835X
Appears in Collections:
Other Diseases

Full metadata record

DC FieldValue Language
dc.contributor.authorLegros, D-
dc.contributor.authorOchola, D-
dc.contributor.authorLwanga, N-
dc.contributor.authorGuma, G-
dc.date.accessioned2008-04-14T11:46:48Z-
dc.date.available2008-04-14T11:46:48Z-
dc.date.issued1998-03-
dc.identifier.citationAntibiotic Sensitivity of Endemic Shigella in Mbarara, Uganda. 1998, 75 (3):160-1notEast Afr Med Jen
dc.identifier.issn0012-835X-
dc.identifier.pmid9640814-
dc.identifier.urihttp://hdl.handle.net/10144/23165-
dc.description.abstractWe analysed the chimio-sensitivity to antibiotics of endemic strains of Shigella isolated in Mbarara district, southwest Uganda. Twenty four strains were isolated, of which none was sensitive to cotrimoxazole and eight (33.4%, 95% CI [15.6-55.3]) to ampicillin, the two antibiotics recommended to treat dysentery during non epidemic periods in Uganda. Two isolates were resistant to nalidixic acid and none was resistant to the fluoroquinolones (Ciprofloxacin, Norfloxacin). It is concluded that the results of this survey could be used to facilitate the elaboration of a new treatment protocol to treat endemic dysentery cases in Uganda.en
dc.language.isoenen
dc.rightsArchived with thanks to East African Medical Journalen
dc.subject.meshAdolescenten
dc.subject.meshAdulten
dc.subject.meshAnti-Bacterial Agentsen
dc.subject.meshChilden
dc.subject.meshChild, Preschoolen
dc.subject.meshCross-Sectional Studiesen
dc.subject.meshDrug Resistance, Microbialen
dc.subject.meshDysentery, Bacillaryen
dc.subject.meshEndemic Diseasesen
dc.subject.meshFecesen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshInfanten
dc.subject.meshMaleen
dc.subject.meshMicrobial Sensitivity Testsen
dc.subject.meshMiddle Ageden
dc.subject.meshUgandaen
dc.titleAntibiotic Sensitivity of Endemic Shigella in Mbarara, Uganda.en
dc.contributor.departmentEpicentre, Kampala, Uganda.en
dc.identifier.journalEast African Medical Journalen

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