Clinical, Microbiological and Antibiotic Susceptibility Patterns of Diarrhoea in Korem, Ethiopia.

Hdl Handle:
http://hdl.handle.net/10144/23166
Title:
Clinical, Microbiological and Antibiotic Susceptibility Patterns of Diarrhoea in Korem, Ethiopia.
Authors:
Desenclos, J C; Zergabachew, A; Desmoulins, B; Chouteau, L; Desve, G; Admassu, M
Journal:
The Journal of Tropical Medicine and Hygiene
Abstract:
Two hundred patients with diarrhoea in a rehabilitation camp in Ethiopia were studied in October 1985 to determine the presence of pathogens in the stool and their susceptibility to antibiotics. A total of 42 (21.1%) patients had a positive culture with enterobacteriaceae, the isolation rate was 15.6% for Escherichia coli, 3.5% for Shigella spp. and 2.01% for Salmonella spp. In-vitro antibiotic resistance was frequent among the 42 isolates: 53% of E. coli strains were found to be resistant to ampicillin, 47% to chloramphenicol, 30% to co-trimoxazole and 67% to tetracycline. Of the seven Shigella, three were resistant to chloramphenicol and four to tetracycline. Multidrug resistance (two or more antibiotics) was observed in 52.3% of the 42 isolates. The protocols used for the screening of dysenteric patients for Shigella spp. or Salmonella spp. were found to be specific but poorly sensitive. The opposite was observed for amoebiasis and giardiasis. The responsibility of widespread use of common oral antibiotics is discussed as one of the major factors of antibiotic resistance occurrence at Korem.
Affiliation:
Médecins sans Frontières, Paris, France.
Issue Date:
Dec-1988
URI:
http://hdl.handle.net/10144/23166
PubMed ID:
2905012
Language:
en
ISSN:
0022-5304
Appears in Collections:
Other Diseases

Full metadata record

DC FieldValue Language
dc.contributor.authorDesenclos, J C-
dc.contributor.authorZergabachew, A-
dc.contributor.authorDesmoulins, B-
dc.contributor.authorChouteau, L-
dc.contributor.authorDesve, G-
dc.contributor.authorAdmassu, M-
dc.date.accessioned2008-04-14T11:48:36Z-
dc.date.available2008-04-14T11:48:36Z-
dc.date.issued1988-12-
dc.identifier.citationClinical, Microbiological and Antibiotic Susceptibility Patterns of Diarrhoea in Korem, Ethiopia. 1988, 91 (6):296-301notJ Trop Med Hygen
dc.identifier.issn0022-5304-
dc.identifier.pmid2905012-
dc.identifier.urihttp://hdl.handle.net/10144/23166-
dc.description.abstractTwo hundred patients with diarrhoea in a rehabilitation camp in Ethiopia were studied in October 1985 to determine the presence of pathogens in the stool and their susceptibility to antibiotics. A total of 42 (21.1%) patients had a positive culture with enterobacteriaceae, the isolation rate was 15.6% for Escherichia coli, 3.5% for Shigella spp. and 2.01% for Salmonella spp. In-vitro antibiotic resistance was frequent among the 42 isolates: 53% of E. coli strains were found to be resistant to ampicillin, 47% to chloramphenicol, 30% to co-trimoxazole and 67% to tetracycline. Of the seven Shigella, three were resistant to chloramphenicol and four to tetracycline. Multidrug resistance (two or more antibiotics) was observed in 52.3% of the 42 isolates. The protocols used for the screening of dysenteric patients for Shigella spp. or Salmonella spp. were found to be specific but poorly sensitive. The opposite was observed for amoebiasis and giardiasis. The responsibility of widespread use of common oral antibiotics is discussed as one of the major factors of antibiotic resistance occurrence at Korem.en
dc.language.isoenen
dc.rightsArchived with thanks to The Journal of Tropical Medicine and Hygieneen
dc.subject.meshAdolescenten
dc.subject.meshAdulten
dc.subject.meshAgeden
dc.subject.meshAnimalsen
dc.subject.meshChilden
dc.subject.meshChild, Preschoolen
dc.subject.meshDiarrheaen
dc.subject.meshDrug Resistance, Microbialen
dc.subject.meshDysenteryen
dc.subject.meshDysentery, Amebicen
dc.subject.meshEntamoeba histolyticaen
dc.subject.meshEnterobacteriaceaeen
dc.subject.meshEnterobacteriaceae Infectionsen
dc.subject.meshEthiopiaen
dc.subject.meshFecesen
dc.subject.meshFemaleen
dc.subject.meshGiardiaen
dc.subject.meshGiardiasisen
dc.subject.meshHumansen
dc.subject.meshInfanten
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.titleClinical, Microbiological and Antibiotic Susceptibility Patterns of Diarrhoea in Korem, Ethiopia.en
dc.contributor.departmentMédecins sans Frontières, Paris, France.en
dc.identifier.journalThe Journal of Tropical Medicine and Hygieneen

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