Sodium Stibogluconate (SSG) & Paromomycin Combination Compared to SSG for Visceral Leishmaniasis in East Africa: A Randomised Controlled Trial

Hdl Handle:
http://hdl.handle.net/10144/242363
Title:
Sodium Stibogluconate (SSG) & Paromomycin Combination Compared to SSG for Visceral Leishmaniasis in East Africa: A Randomised Controlled Trial
Authors:
Musa, Ahmed; Khalil, Eltahir; Hailu, Asrat; Olobo, Joseph; Balasegaram, Manica; Omollo, Raymond; Edwards, Tansy; Rashid, Juma; Mbui, Jane; Musa, Brima; Abuzaid, Abuzaid Abdalla; Ahmed, Osama; Fadlalla, Ahmed; El-Hassan, Ahmed; Mueller, Marius; Mucee, Geoffrey; Njoroge, Simon; Manduku, Veronica; Mutuma, Geoffrey; Apadet, Lilian; Lodenyo, Hudson; Mutea, Dedan; Kirigi, George; Yifru, Sisay; Mengistu, Getahun; Hurissa, Zewdu; Hailu, Workagegnehu; Weldegebreal, Teklu; Tafes, Hailemariam; Mekonnen, Yalemtsehay; Makonnen, Eyasu; Ndegwa, Serah; Sagaki, Patrick; Kimutai, Robert; Kesusu, Josephine; Owiti, Rhoda; Ellis, Sally; Wasunna, Monique
Journal:
PLoS Neglected Tropical Diseases
Abstract:
Alternative treatments for visceral leishmaniasis (VL) are required in East Africa. Paromomycin sulphate (PM) has been shown to be efficacious for VL treatment in India.
Affiliation:
Institute of Endemic Diseases, University of Khartoum, Khartoum, Sudan; Addis Ababa University, Addis Ababa, Ethiopia; Makerere University, Kampala, Uganda; Médecins Sans Frontières-Holland, Amsterdam, The Netherlands; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland; MRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, London, United Kingdom; Centre for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya; Faculty of Medicine, Gedaref University, Gedaref, Sudan; Gondar University, Gondar, Ethiopia; Arba Minch Hospital, Regional Health Bureau of SNNPR State, Arba Minch, Ethiopia; University of Nairobi, Nairobi, Kenya; Amudat Hospital, Amudat, Uganda
Publisher:
Public Library of Science
Issue Date:
Jun-2012
URI:
http://hdl.handle.net/10144/242363
DOI:
10.1371/journal.pntd.0001674
PubMed ID:
22724029
Additional Links:
http://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0001674
Submitted date:
2011-10-11
Type:
Article
Language:
en
ISSN:
1935-2735
Appears in Collections:
Leishmaniasis/Kala Azar

Full metadata record

DC FieldValue Language
dc.contributor.authorMusa, Ahmeden_GB
dc.contributor.authorKhalil, Eltahiren_GB
dc.contributor.authorHailu, Asraten_GB
dc.contributor.authorOlobo, Josephen_GB
dc.contributor.authorBalasegaram, Manicaen_GB
dc.contributor.authorOmollo, Raymonden_GB
dc.contributor.authorEdwards, Tansyen_GB
dc.contributor.authorRashid, Jumaen_GB
dc.contributor.authorMbui, Janeen_GB
dc.contributor.authorMusa, Brimaen_GB
dc.contributor.authorAbuzaid, Abuzaid Abdallaen_GB
dc.contributor.authorAhmed, Osamaen_GB
dc.contributor.authorFadlalla, Ahmeden_GB
dc.contributor.authorEl-Hassan, Ahmeden_GB
dc.contributor.authorMueller, Mariusen_GB
dc.contributor.authorMucee, Geoffreyen_GB
dc.contributor.authorNjoroge, Simonen_GB
dc.contributor.authorManduku, Veronicaen_GB
dc.contributor.authorMutuma, Geoffreyen_GB
dc.contributor.authorApadet, Lilianen_GB
dc.contributor.authorLodenyo, Hudsonen_GB
dc.contributor.authorMutea, Dedanen_GB
dc.contributor.authorKirigi, Georgeen_GB
dc.contributor.authorYifru, Sisayen_GB
dc.contributor.authorMengistu, Getahunen_GB
dc.contributor.authorHurissa, Zewduen_GB
dc.contributor.authorHailu, Workagegnehuen_GB
dc.contributor.authorWeldegebreal, Tekluen_GB
dc.contributor.authorTafes, Hailemariamen_GB
dc.contributor.authorMekonnen, Yalemtsehayen_GB
dc.contributor.authorMakonnen, Eyasuen_GB
dc.contributor.authorNdegwa, Serahen_GB
dc.contributor.authorSagaki, Patricken_GB
dc.contributor.authorKimutai, Roberten_GB
dc.contributor.authorKesusu, Josephineen_GB
dc.contributor.authorOwiti, Rhodaen_GB
dc.contributor.authorEllis, Sallyen_GB
dc.contributor.authorWasunna, Moniqueen_GB
dc.date.accessioned2012-09-10T19:50:19Z-
dc.date.available2012-09-10T19:50:19Z-
dc.date.issued2012-06-
dc.date.submitted2011-10-11-
dc.identifier.citationPLoS Negl Trop Dis. 2012 Jun;6(6):e1674en_GB
dc.identifier.issn1935-2735-
dc.identifier.pmid22724029-
dc.identifier.doi10.1371/journal.pntd.0001674-
dc.identifier.urihttp://hdl.handle.net/10144/242363-
dc.description.abstractAlternative treatments for visceral leishmaniasis (VL) are required in East Africa. Paromomycin sulphate (PM) has been shown to be efficacious for VL treatment in India.en_GB
dc.language.isoenen
dc.publisherPublic Library of Scienceen_GB
dc.relation.urlhttp://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0001674en_GB
dc.rightsArchived with thanks to PLoS Neglected Tropical Diseases and Open Accessen_GB
dc.subjectvisceral leishmaniasiaen_GB
dc.titleSodium Stibogluconate (SSG) & Paromomycin Combination Compared to SSG for Visceral Leishmaniasis in East Africa: A Randomised Controlled Trialen
dc.typeArticleen
dc.contributor.departmentInstitute of Endemic Diseases, University of Khartoum, Khartoum, Sudan; Addis Ababa University, Addis Ababa, Ethiopia; Makerere University, Kampala, Uganda; Médecins Sans Frontières-Holland, Amsterdam, The Netherlands; Drugs for Neglected Diseases initiative (DNDi), Geneva, Switzerland; MRC Tropical Epidemiology Group, London School of Hygiene and Tropical Medicine, London, United Kingdom; Centre for Clinical Research, Kenya Medical Research Institute, Nairobi, Kenya; Faculty of Medicine, Gedaref University, Gedaref, Sudan; Gondar University, Gondar, Ethiopia; Arba Minch Hospital, Regional Health Bureau of SNNPR State, Arba Minch, Ethiopia; University of Nairobi, Nairobi, Kenya; Amudat Hospital, Amudat, Ugandaen_GB
dc.identifier.journalPLoS Neglected Tropical Diseasesen_GB
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