Lessons and challenges for measles control from unexpected large outbreak, Malawi

Hdl Handle:
http://hdl.handle.net/10144/270740
Title:
Lessons and challenges for measles control from unexpected large outbreak, Malawi
Authors:
Minetti, Andrea; Kagoli, Matthew; Katsulukuta, Agnes; Huerga, Helena; Featherstone, Amber; Chiotcha, Hazel; Noel, Delphine; Bopp, Cameron; Sury, Laurent; Fricke, Renzo; Iscla, Marta; Hurtado, Northan; Ducomble, Tanya; Nicholas, Sarala; Kabuluzi, Storn; Grais, Rebecca F; Luquero, Francisco J
Journal:
Emerging infectious diseases
Abstract:
Despite high reported coverage for routine and supplementary immunization, in 2010 in Malawi, a large measles outbreak occurred that comprised 134,000 cases and 304 deaths. Although the highest attack rates were for young children (2.3%, 7.6%, and 4.5% for children <6, 6-8, and 9-11 months, respectively), persons >15 years of age were highly affected (1.0% and 0.4% for persons 15-19 and >19 years, respectively; 28% of all cases). A survey in 8 districts showed routine coverage of 95.0% for children 12-23 months; 57.9% for children 9-11 months; and 60.7% for children covered during the last supplementary immunization activities in 2008. Vaccine effectiveness was 83.9% for 1 dose and 90.5% for 2 doses. A continuous accumulation of susceptible persons during the past decade probably accounts for this outbreak. Countries en route to measles elimination, such as Malawi, should improve outbreak preparedness. Timeliness and the population chosen are crucial elements for reactive campaigns.
Affiliation:
Epicentre, Paris, France; Ministry of Health, Lilongwe, Malawi; Médecins Sans Frontières, Lilongwe; Médecins Sans Frontières, Paris, France; Médecins Sans Frontières, Brussels, Belgium; Médecins Sans Frontières, Barcelona, Spain.
Publisher:
Center for Disease Control and Prevention
Issue Date:
1-Feb-2013
URI:
http://hdl.handle.net/10144/270740
DOI:
10.3201/eid1902.120301
PubMed ID:
23343504
Additional Links:
http://wwwnc.cdc.gov/eid/article/19/2/12-0301_article.htm
Type:
Article
Language:
en
ISSN:
1080-6059
Appears in Collections:
Other Diseases

Full metadata record

DC FieldValue Language
dc.contributor.authorMinetti, Andreaen_GB
dc.contributor.authorKagoli, Matthewen_GB
dc.contributor.authorKatsulukuta, Agnesen_GB
dc.contributor.authorHuerga, Helenaen_GB
dc.contributor.authorFeatherstone, Amberen_GB
dc.contributor.authorChiotcha, Hazelen_GB
dc.contributor.authorNoel, Delphineen_GB
dc.contributor.authorBopp, Cameronen_GB
dc.contributor.authorSury, Laurenten_GB
dc.contributor.authorFricke, Renzoen_GB
dc.contributor.authorIscla, Martaen_GB
dc.contributor.authorHurtado, Northanen_GB
dc.contributor.authorDucomble, Tanyaen_GB
dc.contributor.authorNicholas, Saralaen_GB
dc.contributor.authorKabuluzi, Stornen_GB
dc.contributor.authorGrais, Rebecca Fen_GB
dc.contributor.authorLuquero, Francisco Jen_GB
dc.date.accessioned2013-02-28T23:42:16Z-
dc.date.available2013-02-28T23:42:16Z-
dc.date.issued2013-02-01-
dc.identifier.citationEmerging Infect. Dis. 2013;19(2):202-9en_GB
dc.identifier.issn1080-6059-
dc.identifier.pmid23343504-
dc.identifier.doi10.3201/eid1902.120301-
dc.identifier.urihttp://hdl.handle.net/10144/270740-
dc.description.abstractDespite high reported coverage for routine and supplementary immunization, in 2010 in Malawi, a large measles outbreak occurred that comprised 134,000 cases and 304 deaths. Although the highest attack rates were for young children (2.3%, 7.6%, and 4.5% for children <6, 6-8, and 9-11 months, respectively), persons >15 years of age were highly affected (1.0% and 0.4% for persons 15-19 and >19 years, respectively; 28% of all cases). A survey in 8 districts showed routine coverage of 95.0% for children 12-23 months; 57.9% for children 9-11 months; and 60.7% for children covered during the last supplementary immunization activities in 2008. Vaccine effectiveness was 83.9% for 1 dose and 90.5% for 2 doses. A continuous accumulation of susceptible persons during the past decade probably accounts for this outbreak. Countries en route to measles elimination, such as Malawi, should improve outbreak preparedness. Timeliness and the population chosen are crucial elements for reactive campaigns.en_GB
dc.language.isoenen
dc.publisherCenter for Disease Control and Preventionen_GB
dc.relation.urlhttp://wwwnc.cdc.gov/eid/article/19/2/12-0301_article.htmen_GB
dc.rightsPublished by Centers for Disease Control (CDC) Archived on this site by permission of CDC, http://www.cdc.gov/ncidod/eiden_GB
dc.titleLessons and challenges for measles control from unexpected large outbreak, Malawien
dc.typeArticleen
dc.contributor.departmentEpicentre, Paris, France; Ministry of Health, Lilongwe, Malawi; Médecins Sans Frontières, Lilongwe; Médecins Sans Frontières, Paris, France; Médecins Sans Frontières, Brussels, Belgium; Médecins Sans Frontières, Barcelona, Spain.en_GB
dc.identifier.journalEmerging infectious diseasesen_GB

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