Early prediction of treatment efficacy in Second-Stage Gambiense Human African Trypanosomiasis

Hdl Handle:
http://hdl.handle.net/10144/272032
Title:
Early prediction of treatment efficacy in Second-Stage Gambiense Human African Trypanosomiasis
Authors:
Priotto, G; Chappuis, F; Bastard, M; Flevaud, L; Etard, J-F
Journal:
PLoS Neglected Tropical Diseases
Abstract:
Human African trypanosomiasis is fatal without treatment. The long post-treatment follow-up (24 months) required to assess cure complicates patient management and is a major obstacle in the development of new therapies. We analyzed individual patient data from 12 programs conducted by Médecins Sans Frontières in Uganda, Sudan, Angola, Central African Republic, Republic of Congo and Democratic Republic of Congo searching for early efficacy indicators.
Affiliation:
Epicentre, Paris, France. gpriotto@neuf.fr
Issue Date:
5-Jun-2012
URI:
http://hdl.handle.net/10144/272032
DOI:
10.1371/journal.pntd.0001662
PubMed ID:
22701752
Language:
en
ISSN:
1935-2735
Appears in Collections:
Trypanosomiasis/Sleeping Sickness

Full metadata record

DC FieldValue Language
dc.contributor.authorPriotto, Gen_GB
dc.contributor.authorChappuis, Fen_GB
dc.contributor.authorBastard, Men_GB
dc.contributor.authorFlevaud, Len_GB
dc.contributor.authorEtard, J-Fen_GB
dc.date.accessioned2013-03-13T12:16:44Z-
dc.date.available2013-03-13T12:16:44Z-
dc.date.issued2012-06-05-
dc.identifier.citationEarly prediction of treatment efficacy in second-stage gambiense human African trypanosomiasis. 2012, 6 (6):e1662 PLoS Negl Trop Disen_GB
dc.identifier.issn1935-2735-
dc.identifier.pmid22701752-
dc.identifier.doi10.1371/journal.pntd.0001662-
dc.identifier.urihttp://hdl.handle.net/10144/272032-
dc.description.abstractHuman African trypanosomiasis is fatal without treatment. The long post-treatment follow-up (24 months) required to assess cure complicates patient management and is a major obstacle in the development of new therapies. We analyzed individual patient data from 12 programs conducted by Médecins Sans Frontières in Uganda, Sudan, Angola, Central African Republic, Republic of Congo and Democratic Republic of Congo searching for early efficacy indicators.en_GB
dc.language.isoenen
dc.rightsArchived with thanks to PLoS Neglected Tropical Diseasesen_GB
dc.subject.meshAdolescenten_GB
dc.subject.meshAdulten_GB
dc.subject.meshAfricaen_GB
dc.subject.meshCerebrospinal Fluiden_GB
dc.subject.meshDrug Monitoringen_GB
dc.subject.meshFemaleen_GB
dc.subject.meshHumansen_GB
dc.subject.meshLeukocyte Counten_GB
dc.subject.meshMaleen_GB
dc.subject.meshSensitivity and Specificityen_GB
dc.subject.meshTime Factorsen_GB
dc.subject.meshTreatment Outcomeen_GB
dc.subject.meshTrypanosoma brucei gambienseen_GB
dc.subject.meshTrypanosomiasis, Africanen_GB
dc.subject.meshYoung Adulten_GB
dc.titleEarly prediction of treatment efficacy in Second-Stage Gambiense Human African Trypanosomiasisen
dc.contributor.departmentEpicentre, Paris, France. gpriotto@neuf.fren_GB
dc.identifier.journalPLoS Neglected Tropical Diseasesen_GB

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