Diphtheria outbreak with high mortality in northeastern Nigeria

Hdl Handle:
http://hdl.handle.net/10144/303703
Title:
Diphtheria outbreak with high mortality in northeastern Nigeria
Authors:
Besa, N C; Coldiron, M E; Bakri, A; Raji, A; Nsuami, M J; Rousseau, C; Hurtado, N; Porten, K
Journal:
Epidemiology and Infection
Abstract:
SUMMARY A diphtheria outbreak occurred from February to November 2011 in the village of Kimba and its surrounding settlements, in Borno State, northeastern Nigeria. We conducted a retrospective outbreak investigation in Kimba village and the surrounding settlements to better describe the extent and clinical characteristics of this outbreak. Ninety-eight cases met the criteria of the case definition of diphtheria, 63 (64·3%) of whom were children aged <10 years; 98% of cases had never been immunized against diphtheria. None of the 98 cases received diphtheria antitoxin, penicillin, or erythromycin during their illness. The overall case-fatality ratio was 21·4%, and was highest in children aged 0-4 years (42·9%). Low rates of immunization, delayed clinical recognition of diphtheria and absence of treatment with antitoxin and appropriate antibiotics contributed to this epidemic and its severity.
Affiliation:
Epicentre, Paris, France.
Publisher:
Cambridge University Press
Issue Date:
18-Jul-2013
URI:
http://hdl.handle.net/10144/303703
DOI:
10.1017/S0950268813001696
PubMed ID:
23866913
Language:
en
ISSN:
1469-4409
Appears in Collections:
Other Diseases

Full metadata record

DC FieldValue Language
dc.contributor.authorBesa, N Cen_GB
dc.contributor.authorColdiron, M Een_GB
dc.contributor.authorBakri, Aen_GB
dc.contributor.authorRaji, Aen_GB
dc.contributor.authorNsuami, M Jen_GB
dc.contributor.authorRousseau, Cen_GB
dc.contributor.authorHurtado, Nen_GB
dc.contributor.authorPorten, Ken_GB
dc.date.accessioned2013-10-21T00:57:28Z-
dc.date.available2013-10-21T00:57:28Z-
dc.date.issued2013-07-18-
dc.identifier.citationDiphtheria outbreak with high mortality in northeastern Nigeria. 2013:1-6 Epidemiol. Infect.en_GB
dc.identifier.issn1469-4409-
dc.identifier.pmid23866913-
dc.identifier.doi10.1017/S0950268813001696-
dc.identifier.urihttp://hdl.handle.net/10144/303703-
dc.description.abstractSUMMARY A diphtheria outbreak occurred from February to November 2011 in the village of Kimba and its surrounding settlements, in Borno State, northeastern Nigeria. We conducted a retrospective outbreak investigation in Kimba village and the surrounding settlements to better describe the extent and clinical characteristics of this outbreak. Ninety-eight cases met the criteria of the case definition of diphtheria, 63 (64·3%) of whom were children aged <10 years; 98% of cases had never been immunized against diphtheria. None of the 98 cases received diphtheria antitoxin, penicillin, or erythromycin during their illness. The overall case-fatality ratio was 21·4%, and was highest in children aged 0-4 years (42·9%). Low rates of immunization, delayed clinical recognition of diphtheria and absence of treatment with antitoxin and appropriate antibiotics contributed to this epidemic and its severity.en_GB
dc.languageENG-
dc.language.isoenen
dc.publisherCambridge University Pressen_GB
dc.rightsArchived with thanks to Epidemiology and Infection and Cambridge University Press' open access policyen_GB
dc.subjectInfections, Otheren_GB
dc.subjectOutbreaksen_GB
dc.titleDiphtheria outbreak with high mortality in northeastern Nigeriaen
dc.contributor.departmentEpicentre, Paris, France.en_GB
dc.identifier.journalEpidemiology and Infectionen_GB

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