Pooled HIV-1 Viral Load Testing Using Dried Blood Spots to Reduce the Cost of Monitoring Antiretroviral Treatment in a Resource-Limited Setting

Hdl Handle:
http://hdl.handle.net/10144/305934
Title:
Pooled HIV-1 Viral Load Testing Using Dried Blood Spots to Reduce the Cost of Monitoring Antiretroviral Treatment in a Resource-Limited Setting
Authors:
Pannus, Pieter; Fajardo, Emmanuel; Metcalf, Carol; Coulborn, Rebecca M; Durán, Laura T; Bygrave, Helen; Ellman, Tom; Garone, Daniela; Murowa, Michael; Mwenda, Reuben; Reid, Tony; Preiser, Wolfgang
Journal:
Journal of Acquired Immune Deficiency Syndromes (1999)
Abstract:
: Rollout of routine HIV-1 viral load monitoring is hampered by high costs and logistical difficulties associated with sample collection and transport. New strategies are needed to overcome these constraints. Dried blood spots from finger pricks have been shown to be more practical than the use of plasma specimens, and pooling strategies using plasma specimens have been demonstrated to be an efficient method to reduce costs. This study found that combination of finger-prick dried blood spots and a pooling strategy is a feasible and efficient option to reduce costs, while maintaining accuracy in the context of a district hospital in Malawi.
Affiliation:
*Médecins Sans Frontières, Southern Africa Medical Unit, Cape Town, South Africa; †Médecins Sans Frontières, Thyolo, Malawi; ‡Ministry of Health, Health Technical Support Services, Diagnostics, District Management Office, Thyolo, Malawi; §Ministry of Health, Lilongwe, Malawi; ‖Médecins Sans Frontières, Operational Research Unit, Brussels, Belgium; and ¶Division of Medical Virology, Stellenbosch University, and National Health Laboratory Service, Tygerberg, South Africa.
Publisher:
Lippincott Williams & Wilkins
Issue Date:
1-Oct-2013
URI:
http://hdl.handle.net/10144/305934
DOI:
10.1097/QAI.0b013e3182a61e63
PubMed ID:
23892241
Language:
en
ISSN:
1944-7884
Appears in Collections:
HIV/AIDS

Full metadata record

DC FieldValue Language
dc.contributor.authorPannus, Pieteren_GB
dc.contributor.authorFajardo, Emmanuelen_GB
dc.contributor.authorMetcalf, Carolen_GB
dc.contributor.authorCoulborn, Rebecca Men_GB
dc.contributor.authorDurán, Laura Ten_GB
dc.contributor.authorBygrave, Helenen_GB
dc.contributor.authorEllman, Tomen_GB
dc.contributor.authorGarone, Danielaen_GB
dc.contributor.authorMurowa, Michaelen_GB
dc.contributor.authorMwenda, Reubenen_GB
dc.contributor.authorReid, Tonyen_GB
dc.contributor.authorPreiser, Wolfgangen_GB
dc.date.accessioned2013-11-29T14:18:24Z-
dc.date.available2013-11-29T14:18:24Z-
dc.date.issued2013-10-01-
dc.identifier.citationPooled HIV-1 Viral Load Testing Using Dried Blood Spots to Reduce the Cost of Monitoring Antiretroviral Treatment in a Resource-Limited Setting. 2013, 64 (2):134-7 J. Acquir. Immune Defic. Syndr.en_GB
dc.identifier.issn1944-7884-
dc.identifier.pmid23892241-
dc.identifier.doi10.1097/QAI.0b013e3182a61e63-
dc.identifier.urihttp://hdl.handle.net/10144/305934-
dc.description.abstract: Rollout of routine HIV-1 viral load monitoring is hampered by high costs and logistical difficulties associated with sample collection and transport. New strategies are needed to overcome these constraints. Dried blood spots from finger pricks have been shown to be more practical than the use of plasma specimens, and pooling strategies using plasma specimens have been demonstrated to be an efficient method to reduce costs. This study found that combination of finger-prick dried blood spots and a pooling strategy is a feasible and efficient option to reduce costs, while maintaining accuracy in the context of a district hospital in Malawi.en_GB
dc.language.isoenen
dc.publisherLippincott Williams & Wilkinsen_GB
dc.rightsArchived with thanks to Journal of Acquired Immune Deficiency Syndromes (1999)en_GB
dc.subjectHIV/AIDSen_GB
dc.subjectPooled Viral Load testingen_GB
dc.subjectDried blood spotsen_GB
dc.titlePooled HIV-1 Viral Load Testing Using Dried Blood Spots to Reduce the Cost of Monitoring Antiretroviral Treatment in a Resource-Limited Settingen
dc.contributor.department*Médecins Sans Frontières, Southern Africa Medical Unit, Cape Town, South Africa; †Médecins Sans Frontières, Thyolo, Malawi; ‡Ministry of Health, Health Technical Support Services, Diagnostics, District Management Office, Thyolo, Malawi; §Ministry of Health, Lilongwe, Malawi; ‖Médecins Sans Frontières, Operational Research Unit, Brussels, Belgium; and ¶Division of Medical Virology, Stellenbosch University, and National Health Laboratory Service, Tygerberg, South Africa.en_GB
dc.identifier.journalJournal of Acquired Immune Deficiency Syndromes (1999)en_GB

Related articles on PubMed

All Items in MSF are protected by copyright, with all rights reserved, unless otherwise indicated.