The value of and challenges for cholera vaccines in Africa.

Hdl Handle:
http://hdl.handle.net/10144/306062
Title:
The value of and challenges for cholera vaccines in Africa.
Authors:
von Seidlein, L; Jiddawi, M; Grais, R; Luquero, F J; Lucas, M; Deen, J
Journal:
Journal of Infectious Diseases
Abstract:
The 21st century saw a shift in the cholera burden from Asia to Africa. The risk factors for cholera outbreaks in Africa are incompletely understood, and the traditional emphasis on providing safe drinking water and improving sanitation and hygiene has proven remarkably insufficient to contain outbreaks. Current killed whole-cell oral cholera vaccines (OCVs) are safe and guarantee a high level of protection for several years. OCVs have been licensed for >20 years, but their potential for preventing and control cholera outbreaks in Africa has not been realized. Although each item in the long list of technical reasons why cholera vaccination campaigns have been deferred is plausible, we believe that the biggest barrier is that populations affected by cholera outbreaks are underprivileged and lack a strong political voice. The evaluation and use of OCVs as a tool for cholera control will require a new, more compassionate, less risk-averse generation of decision makers.
Affiliation:
Menzies School of Health Research, Casuarina, Australia.
Issue Date:
Nov-2013
URI:
http://hdl.handle.net/10144/306062
DOI:
10.1093/infdis/jit194
PubMed ID:
24101650
Language:
en
ISSN:
1537-6613
Appears in Collections:
Vaccination

Full metadata record

DC FieldValue Language
dc.contributor.authorvon Seidlein, Len_GB
dc.contributor.authorJiddawi, Men_GB
dc.contributor.authorGrais, Ren_GB
dc.contributor.authorLuquero, F Jen_GB
dc.contributor.authorLucas, Men_GB
dc.contributor.authorDeen, Jen_GB
dc.date.accessioned2013-12-01T09:55:08Z-
dc.date.available2013-12-01T09:55:08Z-
dc.date.issued2013-11-
dc.identifier.citationThe value of and challenges for cholera vaccines in Africa. 2013, 208 Suppl 1:S8-S14 J. Infect. Dis.en_GB
dc.identifier.issn1537-6613-
dc.identifier.pmid24101650-
dc.identifier.doi10.1093/infdis/jit194-
dc.identifier.urihttp://hdl.handle.net/10144/306062-
dc.description.abstractThe 21st century saw a shift in the cholera burden from Asia to Africa. The risk factors for cholera outbreaks in Africa are incompletely understood, and the traditional emphasis on providing safe drinking water and improving sanitation and hygiene has proven remarkably insufficient to contain outbreaks. Current killed whole-cell oral cholera vaccines (OCVs) are safe and guarantee a high level of protection for several years. OCVs have been licensed for >20 years, but their potential for preventing and control cholera outbreaks in Africa has not been realized. Although each item in the long list of technical reasons why cholera vaccination campaigns have been deferred is plausible, we believe that the biggest barrier is that populations affected by cholera outbreaks are underprivileged and lack a strong political voice. The evaluation and use of OCVs as a tool for cholera control will require a new, more compassionate, less risk-averse generation of decision makers.en_GB
dc.language.isoenen
dc.rightsPublished by Infectious Diseases Society of America Archived on this site with permission and copyright 2013 by the Infectious Diseases Society of America, [url] and Oxford University Pressen_GB
dc.subjectCholeraen_GB
dc.subjectVaccinesen_GB
dc.subjectAfricaen_GB
dc.titleThe value of and challenges for cholera vaccines in Africa.en
dc.contributor.departmentMenzies School of Health Research, Casuarina, Australia.en_GB
dc.identifier.journalJournal of Infectious Diseasesen_GB

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