Five-Year Field Results and Long-Term Effectiveness of 20 mg/kg Liposomal Amphotericin B (Ambisome) for Visceral Leishmaniasis in Bihar, India

Hdl Handle:
http://hdl.handle.net/10144/311611
Title:
Five-Year Field Results and Long-Term Effectiveness of 20 mg/kg Liposomal Amphotericin B (Ambisome) for Visceral Leishmaniasis in Bihar, India
Authors:
Burza, Sakib; Sinha, Prabhat K; Mahajan, Raman; Lima, María Angeles; Mitra, Gaurab; Verma, Neena; Balasegarem, Manica; Das, Pradeep
Journal:
PLoS Neglected Tropical Diseases
Abstract:
Visceral Leishmaniasis (VL; also known as Kala-azar) is an ultimately fatal disease endemic in Bihar. A 2007 observational cohort study in Bihar of 251 patients with VL treated with 20 mg/Kg intravenous liposomal amphotericin B (Ambisome) demonstrated a 98% cure rate at 6-months. Between July 2007 and August 2012, Médecins Sans Frontières (MSF) and the Rajendra Memorial Research Institute (RMRI) implemented a VL treatment project in Bihar, India-an area highly endemic for Leishmania donovani-using this regimen as first-line treatment.
Publisher:
Public Library of Science
Issue Date:
Jan-2014
URI:
http://hdl.handle.net/10144/311611
DOI:
10.1371/journal.pntd.0002603
PubMed ID:
24392168
Language:
en
ISSN:
1935-2735
Appears in Collections:
Leishmaniasis/Kala Azar

Full metadata record

DC FieldValue Language
dc.contributor.authorBurza, Sakiben_GB
dc.contributor.authorSinha, Prabhat Ken_GB
dc.contributor.authorMahajan, Ramanen_GB
dc.contributor.authorLima, María Angelesen_GB
dc.contributor.authorMitra, Gauraben_GB
dc.contributor.authorVerma, Neenaen_GB
dc.contributor.authorBalasegarem, Manicaen_GB
dc.contributor.authorDas, Pradeepen_GB
dc.date.accessioned2014-01-20T21:27:02Z-
dc.date.available2014-01-20T21:27:02Z-
dc.date.issued2014-01-
dc.identifier.citationFive-Year Field Results and Long-Term Effectiveness of 20 mg/kg Liposomal Amphotericin B (Ambisome) for Visceral Leishmaniasis in Bihar, India. 2014, 8 (1):e2603 PLoS Negl Trop Disen_GB
dc.identifier.issn1935-2735-
dc.identifier.pmid24392168-
dc.identifier.doi10.1371/journal.pntd.0002603-
dc.identifier.urihttp://hdl.handle.net/10144/311611-
dc.description.abstractVisceral Leishmaniasis (VL; also known as Kala-azar) is an ultimately fatal disease endemic in Bihar. A 2007 observational cohort study in Bihar of 251 patients with VL treated with 20 mg/Kg intravenous liposomal amphotericin B (Ambisome) demonstrated a 98% cure rate at 6-months. Between July 2007 and August 2012, Médecins Sans Frontières (MSF) and the Rajendra Memorial Research Institute (RMRI) implemented a VL treatment project in Bihar, India-an area highly endemic for Leishmania donovani-using this regimen as first-line treatment.en_GB
dc.language.isoenen
dc.publisherPublic Library of Scienceen_GB
dc.rightsArchived with thanks to PLoS Neglected Tropical Diseasesen_GB
dc.subjectKala Azar/Visceral Leishmaniasisen_GB
dc.titleFive-Year Field Results and Long-Term Effectiveness of 20 mg/kg Liposomal Amphotericin B (Ambisome) for Visceral Leishmaniasis in Bihar, Indiaen
dc.identifier.journalPLoS Neglected Tropical Diseasesen_GB

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