Emergence of Zaire Ebola Virus Disease in Guinea - Preliminary Report

Hdl Handle:
http://hdl.handle.net/10144/326084
Title:
Emergence of Zaire Ebola Virus Disease in Guinea - Preliminary Report
Authors:
Baize, Sylvain; Pannetier, Delphine; Oestereich, Lisa; Rieger, Toni; Koivogui, Lamine; Magassouba, N'faly; Soropogui, Barrè; Sow, Mamadou Saliou; Keïta, Sakoba; De Clerck, Hilde; Tiffany, Amanda; Dominguez, Gemma; Loua, Mathieu; Traoré, Alexis; Kolié, Moussa; Malano, Emmanuel Roland; Heleze, Emmanuel; Bocquin, Anne; Mély, Stephane; Raoul, Hervé; Caro, Valérie; Cadar, Dániel; Gabriel, Martin; Pahlmann, Meike; Tappe, Dennis; Schmidt-Chanasit, Jonas; Impouma, Benido; Diallo, Abdoul Karim; Formenty, Pierre; Van Herp, Michel; Günther, Stephan
Journal:
The New England Journal of Medicine
Abstract:
In March 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea. Virologic investigation identified Zaire ebolavirus (EBOV) as the causative agent. Full-length genome sequencing and phylogenetic analysis showed that EBOV from Guinea forms a separate clade in relationship to the known EBOV strains from the Democratic Republic of Congo and Gabon. Epidemiologic investigation linked the laboratory-confirmed cases with the presumed first fatality of the outbreak in December 2013. This study demonstrates the emergence of a new EBOV strain in Guinea.
Publisher:
Massachusetts Medical Society
Issue Date:
16-Apr-2014
URI:
http://hdl.handle.net/10144/326084
DOI:
10.1056/NEJMoa1404505
PubMed ID:
24738640
Language:
en
ISSN:
1533-4406
Appears in Collections:
Other Diseases

Full metadata record

DC FieldValue Language
dc.contributor.authorBaize, Sylvainen_GB
dc.contributor.authorPannetier, Delphineen_GB
dc.contributor.authorOestereich, Lisaen_GB
dc.contributor.authorRieger, Tonien_GB
dc.contributor.authorKoivogui, Lamineen_GB
dc.contributor.authorMagassouba, N'falyen_GB
dc.contributor.authorSoropogui, Barrèen_GB
dc.contributor.authorSow, Mamadou Saliouen_GB
dc.contributor.authorKeïta, Sakobaen_GB
dc.contributor.authorDe Clerck, Hildeen_GB
dc.contributor.authorTiffany, Amandaen_GB
dc.contributor.authorDominguez, Gemmaen_GB
dc.contributor.authorLoua, Mathieuen_GB
dc.contributor.authorTraoré, Alexisen_GB
dc.contributor.authorKolié, Moussaen_GB
dc.contributor.authorMalano, Emmanuel Rolanden_GB
dc.contributor.authorHeleze, Emmanuelen_GB
dc.contributor.authorBocquin, Anneen_GB
dc.contributor.authorMély, Stephaneen_GB
dc.contributor.authorRaoul, Hervéen_GB
dc.contributor.authorCaro, Valérieen_GB
dc.contributor.authorCadar, Dánielen_GB
dc.contributor.authorGabriel, Martinen_GB
dc.contributor.authorPahlmann, Meikeen_GB
dc.contributor.authorTappe, Dennisen_GB
dc.contributor.authorSchmidt-Chanasit, Jonasen_GB
dc.contributor.authorImpouma, Benidoen_GB
dc.contributor.authorDiallo, Abdoul Karimen_GB
dc.contributor.authorFormenty, Pierreen_GB
dc.contributor.authorVan Herp, Michelen_GB
dc.contributor.authorGünther, Stephanen_GB
dc.date.accessioned2014-09-11T21:32:33Z-
dc.date.available2014-09-11T21:32:33Z-
dc.date.issued2014-04-16-
dc.identifier.citationEmergence of Zaire Ebola Virus Disease in Guinea - Preliminary Report. 2014: N. Engl. J. Med.en_GB
dc.identifier.issn1533-4406-
dc.identifier.pmid24738640-
dc.identifier.doi10.1056/NEJMoa1404505-
dc.identifier.urihttp://hdl.handle.net/10144/326084-
dc.description.abstractIn March 2014, the World Health Organization was notified of an outbreak of a communicable disease characterized by fever, severe diarrhea, vomiting, and a high fatality rate in Guinea. Virologic investigation identified Zaire ebolavirus (EBOV) as the causative agent. Full-length genome sequencing and phylogenetic analysis showed that EBOV from Guinea forms a separate clade in relationship to the known EBOV strains from the Democratic Republic of Congo and Gabon. Epidemiologic investigation linked the laboratory-confirmed cases with the presumed first fatality of the outbreak in December 2013. This study demonstrates the emergence of a new EBOV strain in Guinea.en_GB
dc.languageENG-
dc.language.isoenen
dc.publisherMassachusetts Medical Societyen_GB
dc.rightsArchived with thanks to The New England Journal of Medicineen_GB
dc.subjectInfections, Viralen_GB
dc.subjectOutbreaksen_GB
dc.titleEmergence of Zaire Ebola Virus Disease in Guinea - Preliminary Reporten
dc.identifier.journalThe New England Journal of Medicineen_GB

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