Expanding Access to HIV Viral Load Testing: A Systematic Review of RNA Stability in EDTA Tubes and PPT beyond Current Time and Temperature Thresholds

Hdl Handle:
http://hdl.handle.net/10144/337713
Title:
Expanding Access to HIV Viral Load Testing: A Systematic Review of RNA Stability in EDTA Tubes and PPT beyond Current Time and Temperature Thresholds
Authors:
Bonner, Kimberly; Siemieniuk, Reed A; Boozary, Andrew; Roberts, Teri; Fajardo, Emmanuel; Cohn, Jennifer
Journal:
PLoS One
Abstract:
HIV viral load (VL) testing is the gold standard for antiretroviral treatment monitoring, but many barriers exist to VL testing in resource-limited settings, including storage and transport limitations for whole blood and plasma. Data from various studies indicate that HIV RNA is stable beyond current recommendations. We conducted a systematic review to assess stability data of HIV RNA in whole blood and plasma across times and temperatures.
Publisher:
Public Library of Science
Issue Date:
1-Dec-2014
URI:
http://hdl.handle.net/10144/337713
DOI:
10.1371/journal.pone.0113813
PubMed ID:
25437009
Language:
en
ISSN:
1932-6203
Appears in Collections:
HIV/AIDS

Full metadata record

DC FieldValue Language
dc.contributor.authorBonner, Kimberlyen_GB
dc.contributor.authorSiemieniuk, Reed Aen_GB
dc.contributor.authorBoozary, Andrewen_GB
dc.contributor.authorRoberts, Terien_GB
dc.contributor.authorFajardo, Emmanuelen_GB
dc.contributor.authorCohn, Jenniferen_GB
dc.date.accessioned2014-12-30T23:54:13Z-
dc.date.available2014-12-30T23:54:13Z-
dc.date.issued2014-12-01-
dc.identifier.citationExpanding Access to HIV Viral Load Testing: A Systematic Review of RNA Stability in EDTA Tubes and PPT beyond Current Time and Temperature Thresholds. 2014, 9 (12):e113813 PLoS ONEen_GB
dc.identifier.issn1932-6203-
dc.identifier.pmid25437009-
dc.identifier.doi10.1371/journal.pone.0113813-
dc.identifier.urihttp://hdl.handle.net/10144/337713-
dc.description.abstractHIV viral load (VL) testing is the gold standard for antiretroviral treatment monitoring, but many barriers exist to VL testing in resource-limited settings, including storage and transport limitations for whole blood and plasma. Data from various studies indicate that HIV RNA is stable beyond current recommendations. We conducted a systematic review to assess stability data of HIV RNA in whole blood and plasma across times and temperatures.en_GB
dc.language.isoenen
dc.publisherPublic Library of Scienceen_GB
dc.rightsPublished by Public Library of Science, [url]http://www.plosone.org/[/url] Archived on this site by Open Access permissionen_GB
dc.titleExpanding Access to HIV Viral Load Testing: A Systematic Review of RNA Stability in EDTA Tubes and PPT beyond Current Time and Temperature Thresholdsen
dc.identifier.journalPLoS Oneen_GB

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