Mycobacterium ulcerans treatment - can antibiotic duration be reduced in selected patients?

Hdl Handle:
http://hdl.handle.net/10144/347023
Title:
Mycobacterium ulcerans treatment - can antibiotic duration be reduced in selected patients?
Authors:
Cowan, Raquel; Athan, Eugene; Friedman, N Deborah; Hughes, Andrew J; McDonald, Anthony; Callan, Peter; Fyfe, Janet; O'Brien, Daniel P
Journal:
PLoS Neglected Tropical Diseases
Abstract:
Mycobacterium ulcerans (M. ulcerans) is a necrotizing skin infection endemic to the Bellarine Peninsula, Australia. Current treatment recommendations include 8 weeks of combination antibiotics, with adjuvant surgery if necessary. However, antibiotic toxicity often results in early treatment cessation and local experience suggests that shorter antibiotic courses may be effective with concurrent surgery. We report the outcomes of patients in the Barwon Health M. ulcerans cohort who received shorter courses of antibiotic therapy than 8 weeks.
Publisher:
Public Library of Science
Issue Date:
6-Feb-2015
URI:
http://hdl.handle.net/10144/347023
DOI:
10.1371/journal.pntd.0003503
PubMed ID:
25658304
Language:
en
ISSN:
1935-2735
Appears in Collections:
Other Diseases

Full metadata record

DC FieldValue Language
dc.contributor.authorCowan, Raquelen_GB
dc.contributor.authorAthan, Eugeneen_GB
dc.contributor.authorFriedman, N Deborahen_GB
dc.contributor.authorHughes, Andrew Jen_GB
dc.contributor.authorMcDonald, Anthonyen_GB
dc.contributor.authorCallan, Peteren_GB
dc.contributor.authorFyfe, Janeten_GB
dc.contributor.authorO'Brien, Daniel Pen_GB
dc.date.accessioned2015-03-23T19:09:58Z-
dc.date.available2015-03-23T19:09:58Z-
dc.date.issued2015-02-06-
dc.identifier.citationMycobacterium ulcerans treatment - can antibiotic duration be reduced in selected patients? 2015, 9 (2):e0003503 PLoS Negl Trop Disen_GB
dc.identifier.issn1935-2735-
dc.identifier.pmid25658304-
dc.identifier.doi10.1371/journal.pntd.0003503-
dc.identifier.urihttp://hdl.handle.net/10144/347023-
dc.description.abstractMycobacterium ulcerans (M. ulcerans) is a necrotizing skin infection endemic to the Bellarine Peninsula, Australia. Current treatment recommendations include 8 weeks of combination antibiotics, with adjuvant surgery if necessary. However, antibiotic toxicity often results in early treatment cessation and local experience suggests that shorter antibiotic courses may be effective with concurrent surgery. We report the outcomes of patients in the Barwon Health M. ulcerans cohort who received shorter courses of antibiotic therapy than 8 weeks.en_GB
dc.language.isoenen
dc.publisherPublic Library of Scienceen_GB
dc.rightsArchived with thanks to PLoS Neglected Tropical Diseasesen_GB
dc.titleMycobacterium ulcerans treatment - can antibiotic duration be reduced in selected patients?en
dc.identifier.journalPLoS Neglected Tropical Diseasesen_GB

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