Substandard medicines in resource-poor settings: A problem that can no longer be ignored

Hdl Handle:
http://hdl.handle.net/10144/37334
Title:
Substandard medicines in resource-poor settings: A problem that can no longer be ignored
Authors:
Caudron, J M; Ford, N; Henkens, M; Macé, C; Kiddle-Monroe, R; Pinel, J
Journal:
Tropical Medicine & International Health
Abstract:
The circulation of substandard medicines in the developing world is a serious clinical and public health concern. Problems include under or over concentration of ingredients, contamination, poor quality ingredients, poor stability and inadequate packaging. There are multiple causes. Drugs manufactured for export are not regulated to the same standard as those for domestic use, while regulatory agencies in the less-developed world are poorly equipped to assess and address the problem. A number of recent initiatives have been established to address the problem, most notably the WHO pre-qualification programme. However, much more action is required. Donors should encourage their partners to include more explicit quality requirements in their tender mechanisms, while purchasers should insist that producers and distributors supply drugs that comply with international quality standards. Governments in rich countries should not tolerate the export of substandard pharmaceutical products to poor countries, while developing country governments should improve their ability to detect substandard medicines.
Affiliation:
Médecins Sans Frontières, Geneva, Switzerland; AEDES Foundation, Brussels, Belgium
Issue Date:
8-Jul-2008
URI:
http://hdl.handle.net/10144/37334
DOI:
10.1111/j.1365-3156.2008.02106.x
PubMed ID:
18631318
Additional Links:
http://www3.interscience.wiley.com/journal/120747094/abstract
Submitted date:
2008-08-28
Type:
Article
Language:
en
ISSN:
1365-3156
Appears in Collections:
Pharmacy

Full metadata record

DC FieldValue Language
dc.contributor.authorCaudron, J M-
dc.contributor.authorFord, N-
dc.contributor.authorHenkens, M-
dc.contributor.authorMacé, C-
dc.contributor.authorKiddle-Monroe, R-
dc.contributor.authorPinel, J-
dc.date.accessioned2008-09-05T09:00:58Z-
dc.date.available2008-09-05T09:00:58Z-
dc.date.issued2008-07-08-
dc.date.submitted2008-08-28-
dc.identifier.citationTrop Med Int Health 2008;13(8):1062–72en
dc.identifier.issn1365-3156-
dc.identifier.pmid18631318-
dc.identifier.doi10.1111/j.1365-3156.2008.02106.x-
dc.identifier.urihttp://hdl.handle.net/10144/37334-
dc.description.abstractThe circulation of substandard medicines in the developing world is a serious clinical and public health concern. Problems include under or over concentration of ingredients, contamination, poor quality ingredients, poor stability and inadequate packaging. There are multiple causes. Drugs manufactured for export are not regulated to the same standard as those for domestic use, while regulatory agencies in the less-developed world are poorly equipped to assess and address the problem. A number of recent initiatives have been established to address the problem, most notably the WHO pre-qualification programme. However, much more action is required. Donors should encourage their partners to include more explicit quality requirements in their tender mechanisms, while purchasers should insist that producers and distributors supply drugs that comply with international quality standards. Governments in rich countries should not tolerate the export of substandard pharmaceutical products to poor countries, while developing country governments should improve their ability to detect substandard medicines.en
dc.languageENG-
dc.language.isoenen
dc.relation.urlhttp://www3.interscience.wiley.com/journal/120747094/abstracten
dc.rightsArchived on this site with the kind permission of Wiley-Blackwell, [url]http://www.blackwell-synergy.com/loi/tmi[/url]en
dc.subject.meshPharmaceutic Preparationsen
dc.subject.meshQuality Assurance, Health Careen
dc.subject.meshDrug Contaminationen
dc.subject.meshDeveloping Countriesen
dc.titleSubstandard medicines in resource-poor settings: A problem that can no longer be ignoreden
dc.typeArticleen
dc.contributor.departmentMédecins Sans Frontières, Geneva, Switzerland; AEDES Foundation, Brussels, Belgiumen
dc.identifier.journalTropical Medicine & International Healthen
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