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Biological diagnosis of meningococcal meningitis in the African meningitis belt: current epidemic strategy and new perspectives.
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|Title: ||Biological diagnosis of meningococcal meningitis in the African meningitis belt: current epidemic strategy and new perspectives.|
|Affiliation: ||CERMES, Réseau International Institut Pasteur, PO Box 10887, Niamey, Niger. firstname.lastname@example.org|
|Citation: ||Biological diagnosis of meningococcal meningitis in the African meningitis belt: current epidemic strategy and new perspectives. 2007, 25 Suppl 1:A30-6 Vaccine|
|Issue Date: ||3-Sep-2007 |
|PubMed ID: ||17517452|
|Additional Links: ||http://www.sciencedirect.com/science/journal/0264410X|
|Submitted date: ||2009-03-04|
|Abstract: ||Laboratory diagnosis is an essential component in surveillance of meningococcal epidemics, as it can inform decision-makers of the Neisseria meningitidis serogroup(s) involved and the most appropriate vaccine to be selected for mass vaccination. However, countries most affected face real limitations in laboratory diagnostics, due to lack of resources. We describe current diagnostic tools and examine their cost-effectiveness for use in an epidemic context. The conclusion is that current WHO recommendations to use only the latex agglutination assay (Pastorex) at epidemic onset is cost-effective, but recently developed rapid diagnostic tests for the major epidemic-causing meningococcal serogroups may prove a breakthrough for the future.|
Latex Fixation Tests
Polymerase Chain Reaction
Reproducibility of Results
Sensitivity and Specificity
|Rights: ||Published by Elsevier
Archived on this site with kind permission and copyright 2007 from Elsevier|
|Appears in topics: ||Other Diseases|
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