Selection of Plasmodium Falciparum pfcrt and pfmdr1 Polymorphisms After Treatment with Artesunate-Amodiaquine Fixed Dose Combination or Artemether-Lumefantrine in Liberia

Hdl Handle:
http://hdl.handle.net/10144/618654
Title:
Selection of Plasmodium Falciparum pfcrt and pfmdr1 Polymorphisms After Treatment with Artesunate-Amodiaquine Fixed Dose Combination or Artemether-Lumefantrine in Liberia
Authors:
Otienoburu, SD; Maïga-Ascofaré, O; Schramm, B; Jullien, V; Jones, JJ; Zolia, YM; Houzé, P; Ashley, EA; Kiechel, JR; Guérin, PJ; Le Bras, J; Houzé, S
Journal:
Malaria Journal
Abstract:
Plasmodium falciparum uncomplicated malaria can successfully be treated with an artemisinin-based combination therapy (ACT). However resistance is spreading to the different ACT compounds; the artemisinin derivative and the partner drug. Studies of P. falciparum polymorphisms associated with drug resistance can provide a useful tool to track resistance and guide treatment policy as well as an in-depth understanding of the development and spread of resistance.
Publisher:
BioMed Central (Springer Science)
Issue Date:
5-Sep-2016
URI:
http://hdl.handle.net/10144/618654
DOI:
10.1186/s12936-016-1503-3
PubMed ID:
27596849
Submitted date:
2016-09-12
Language:
en
ISSN:
1475-2875
Appears in Collections:
Malaria

Full metadata record

DC FieldValue Language
dc.contributor.authorOtienoburu, SDen
dc.contributor.authorMaïga-Ascofaré, Oen
dc.contributor.authorSchramm, Ben
dc.contributor.authorJullien, Ven
dc.contributor.authorJones, JJen
dc.contributor.authorZolia, YMen
dc.contributor.authorHouzé, Pen
dc.contributor.authorAshley, EAen
dc.contributor.authorKiechel, JRen
dc.contributor.authorGuérin, PJen
dc.contributor.authorLe Bras, Jen
dc.contributor.authorHouzé, Sen
dc.date.accessioned2016-09-15T15:13:07Z-
dc.date.available2016-09-15T15:13:07Z-
dc.date.issued2016-09-05-
dc.date.submitted2016-09-12-
dc.identifier.citationSelection of Plasmodium falciparum pfcrt and pfmdr1 polymorphisms after treatment with artesunate-amodiaquine fixed dose combination or artemether-lumefantrine in Liberia. 2016, 15:452 Malar. J.en
dc.identifier.issn1475-2875-
dc.identifier.pmid27596849-
dc.identifier.doi10.1186/s12936-016-1503-3-
dc.identifier.urihttp://hdl.handle.net/10144/618654-
dc.description.abstractPlasmodium falciparum uncomplicated malaria can successfully be treated with an artemisinin-based combination therapy (ACT). However resistance is spreading to the different ACT compounds; the artemisinin derivative and the partner drug. Studies of P. falciparum polymorphisms associated with drug resistance can provide a useful tool to track resistance and guide treatment policy as well as an in-depth understanding of the development and spread of resistance.en
dc.language.isoenen
dc.publisherBioMed Central (Springer Science)en
dc.rightsPublished by BioMed Central, [url]http://www.malariajournal.com/[/url] Archived on this site by Open Access permissionen
dc.titleSelection of Plasmodium Falciparum pfcrt and pfmdr1 Polymorphisms After Treatment with Artesunate-Amodiaquine Fixed Dose Combination or Artemether-Lumefantrine in Liberiaen
dc.identifier.journalMalaria Journalen

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