Efficacy of Artemether-Lumefantrine in Relation to Drug Exposure in Children With and Without Severe Acute Malnutrition: an Open Comparative Intervention Study in Mali and Niger

Hdl Handle:
http://hdl.handle.net/10144/618690
Title:
Efficacy of Artemether-Lumefantrine in Relation to Drug Exposure in Children With and Without Severe Acute Malnutrition: an Open Comparative Intervention Study in Mali and Niger
Authors:
Denoeud-Ndam, L; Dicko, A; Baudin, E; Guindo, O; Grandesso, F; Diawara, H; Sissoko, S; Sanogo, K; Traoré, S; Keita, S; Barry, A; de Smet, M; Lasry, E; Smit, M; Wiesner, L; Barnes, KI; Djimde, AA; Guerin, PJ; Grais, RF; Doumbo, OK; Etard, JF
Journal:
BMC Medicine
Abstract:
Severe acute malnutrition (SAM) affects almost all organs and has been associated with reduced intestinal absorption of medicines. However, very limited information is available on the pharmacokinetic properties of antimalarial drugs in this vulnerable population. We assessed artemether-lumefantrine (AL) clinical efficacy in children with SAM compared to those without.
Publisher:
BioMed Central
Issue Date:
24-Oct-2016
URI:
http://hdl.handle.net/10144/618690
DOI:
10.1186/s12916-016-0716-1
PubMed ID:
27776521
Submitted date:
2016-10-31
Language:
en
ISSN:
1741-7015
Appears in Collections:
Malaria

Full metadata record

DC FieldValue Language
dc.contributor.authorDenoeud-Ndam, Len
dc.contributor.authorDicko, Aen
dc.contributor.authorBaudin, Een
dc.contributor.authorGuindo, Oen
dc.contributor.authorGrandesso, Fen
dc.contributor.authorDiawara, Hen
dc.contributor.authorSissoko, Sen
dc.contributor.authorSanogo, Ken
dc.contributor.authorTraoré, Sen
dc.contributor.authorKeita, Sen
dc.contributor.authorBarry, Aen
dc.contributor.authorde Smet, Men
dc.contributor.authorLasry, Een
dc.contributor.authorSmit, Men
dc.contributor.authorWiesner, Len
dc.contributor.authorBarnes, KIen
dc.contributor.authorDjimde, AAen
dc.contributor.authorGuerin, PJen
dc.contributor.authorGrais, RFen
dc.contributor.authorDoumbo, OKen
dc.contributor.authorEtard, JFen
dc.date.accessioned2016-11-06T13:16:09Z-
dc.date.available2016-11-06T13:16:09Z-
dc.date.issued2016-10-24-
dc.date.submitted2016-10-31-
dc.identifier.citationEfficacy of Artemether-Lumefantrine in Relation to Drug Exposure in Children With and Without Severe Acute Malnutrition: an Open Comparative Intervention Study in Mali and Niger. 2016, 14 (1):167 BMC Meden
dc.identifier.issn1741-7015-
dc.identifier.pmid27776521-
dc.identifier.doi10.1186/s12916-016-0716-1-
dc.identifier.urihttp://hdl.handle.net/10144/618690-
dc.description.abstractSevere acute malnutrition (SAM) affects almost all organs and has been associated with reduced intestinal absorption of medicines. However, very limited information is available on the pharmacokinetic properties of antimalarial drugs in this vulnerable population. We assessed artemether-lumefantrine (AL) clinical efficacy in children with SAM compared to those without.en
dc.languageENG-
dc.language.isoenen
dc.publisherBioMed Centralen
dc.rightsArchived with thanks to BMC Medicineen
dc.titleEfficacy of Artemether-Lumefantrine in Relation to Drug Exposure in Children With and Without Severe Acute Malnutrition: an Open Comparative Intervention Study in Mali and Nigeren
dc.identifier.journalBMC Medicineen

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