First Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Disease

Hdl Handle:
http://hdl.handle.net/10144/618787
Title:
First Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Disease
Authors:
Dörnemann, J; Burzio, C; Ronsse, A; Sprecher, A; De Clerck, H; Van Herp, M; Kolié, MC; Yosifiva, V; Caluwaerts, S; McElroy, AK; Antierens, A
Journal:
The Journal of Infectious Diseases
Abstract:
A neonate born to an Ebola virus-positive woman was diagnosed with Ebola virus infection on her first day of life. The patient was treated with monoclonal antibodies (ZMapp), a buffy coat transfusion from an Ebola survivor, and the broad-spectrum antiviral GS-5734. On day 20, a venous blood specimen tested negative for Ebola virus by quantitative reverse-transcription polymerase chain reaction. The patient was discharged in good health on day 33 of life. Further follow-up consultations showed age-appropriate weight gain and neurodevelopment at the age of 12 months. This patient is the first neonate documented to have survived congenital infection with Ebola virus.
Publisher:
Oxford University Press
Issue Date:
9-Jan-2017
URI:
http://hdl.handle.net/10144/618787
DOI:
10.1093/infdis/jiw493
PubMed ID:
28073857
Submitted date:
2017-01-18
Language:
en
ISSN:
1537-6613
Appears in Collections:
Paediatrics

Full metadata record

DC FieldValue Language
dc.contributor.authorDörnemann, Jen
dc.contributor.authorBurzio, Cen
dc.contributor.authorRonsse, Aen
dc.contributor.authorSprecher, Aen
dc.contributor.authorDe Clerck, Hen
dc.contributor.authorVan Herp, Men
dc.contributor.authorKolié, MCen
dc.contributor.authorYosifiva, Ven
dc.contributor.authorCaluwaerts, Sen
dc.contributor.authorMcElroy, AKen
dc.contributor.authorAntierens, Aen
dc.date.accessioned2017-02-17T13:05:25Z-
dc.date.available2017-02-17T13:05:25Z-
dc.date.issued2017-01-09-
dc.date.submitted2017-01-18-
dc.identifier.citationFirst Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Disease. 2017 J. Infect. Dis.en
dc.identifier.issn1537-6613-
dc.identifier.pmid28073857-
dc.identifier.doi10.1093/infdis/jiw493-
dc.identifier.urihttp://hdl.handle.net/10144/618787-
dc.description.abstractA neonate born to an Ebola virus-positive woman was diagnosed with Ebola virus infection on her first day of life. The patient was treated with monoclonal antibodies (ZMapp), a buffy coat transfusion from an Ebola survivor, and the broad-spectrum antiviral GS-5734. On day 20, a venous blood specimen tested negative for Ebola virus by quantitative reverse-transcription polymerase chain reaction. The patient was discharged in good health on day 33 of life. Further follow-up consultations showed age-appropriate weight gain and neurodevelopment at the age of 12 months. This patient is the first neonate documented to have survived congenital infection with Ebola virus.en
dc.language.isoenen
dc.publisherOxford University Pressen
dc.rightsPublished by Infectious Diseases Society of America Archived on this site with permission and copyright 200X by the Infectious Diseases Society of America, [url] and Oxford University Pressen
dc.titleFirst Newborn Baby to Receive Experimental Therapies Survives Ebola Virus Diseaseen
dc.identifier.journalThe Journal of Infectious Diseasesen

Related articles on PubMed

All Items in MSF are protected by copyright, with all rights reserved, unless otherwise indicated.