Ebola Virus Disease: An Update On Current Prevention and Management Strategies

Hdl Handle:
http://hdl.handle.net/10144/618818
Title:
Ebola Virus Disease: An Update On Current Prevention and Management Strategies
Authors:
Trad, MA; Naughton, W; Yeung, A; Mazlin, L; O'sullivan, M; Gilroy, N; Fisher, DA; Stuart, RL
Journal:
Journal of Clinical Virology: The Official Publication of the Pan American Society for Clinical Virology
Abstract:
Ebola virus disease (EVD) is characterised by systemic viral replication, immuno-suppression, abnormal inflammatory responses, large volume fluid and electrolyte losses, and high mortality in under-resourced settings. There are various therapeutic strategies targeting EVD including vaccines utilizing different antigen delivery methods, antibody-based therapies and antiviral drugs. These therapies remain experimental, but received attention following their use particularly in cases treated outside West Africa during the 2014-15 outbreak, in which 20 (80%) out of 25 patients survived. Emerging data from current trials look promising and are undergoing further study, however optimised supportive care remains the key to reducing mortality from EVD.
Publisher:
Elsevier
Issue Date:
11-Nov-2016
URI:
http://hdl.handle.net/10144/618818
DOI:
10.1016/j.jcv.2016.11.005
PubMed ID:
27893999
Submitted date:
2016-12-05
Language:
en
ISSN:
1873-5967
Appears in Collections:
Other Diseases

Full metadata record

DC FieldValue Language
dc.contributor.authorTrad, MAen
dc.contributor.authorNaughton, Wen
dc.contributor.authorYeung, Aen
dc.contributor.authorMazlin, Len
dc.contributor.authorO'sullivan, Men
dc.contributor.authorGilroy, Nen
dc.contributor.authorFisher, DAen
dc.contributor.authorStuart, RLen
dc.date.accessioned2017-02-28T21:51:44Z-
dc.date.available2017-02-28T21:51:44Z-
dc.date.issued2016-11-11-
dc.date.submitted2016-12-05-
dc.identifier.citationEbola Virus Disease: An Update On Current Prevention and Management Strategies. 2016, 86:5-13 J. Clin. Virol.en
dc.identifier.issn1873-5967-
dc.identifier.pmid27893999-
dc.identifier.doi10.1016/j.jcv.2016.11.005-
dc.identifier.urihttp://hdl.handle.net/10144/618818-
dc.description.abstractEbola virus disease (EVD) is characterised by systemic viral replication, immuno-suppression, abnormal inflammatory responses, large volume fluid and electrolyte losses, and high mortality in under-resourced settings. There are various therapeutic strategies targeting EVD including vaccines utilizing different antigen delivery methods, antibody-based therapies and antiviral drugs. These therapies remain experimental, but received attention following their use particularly in cases treated outside West Africa during the 2014-15 outbreak, in which 20 (80%) out of 25 patients survived. Emerging data from current trials look promising and are undergoing further study, however optimised supportive care remains the key to reducing mortality from EVD.en
dc.language.isoenen
dc.publisherElsevieren
dc.rightsArchived with thanks to Journal of Clinical Virology : The Official Publication of the Pan American Society for Clinical Virologyen
dc.titleEbola Virus Disease: An Update On Current Prevention and Management Strategiesen
dc.identifier.journalJournal of Clinical Virology: The Official Publication of the Pan American Society for Clinical Virologyen

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