Diagnostic Preparedness for Infectious Disease Outbreaks

Hdl Handle:
http://hdl.handle.net/10144/618937
Title:
Diagnostic Preparedness for Infectious Disease Outbreaks
Authors:
Perkins, M; Dye, C; Balasegaram, M; Bréchot, C; Mombouli, J; Røttingen, J; Tanner, M; Boehme, C
Journal:
Lancet
Abstract:
Diagnostics are crucial in mitigating the effect of disease outbreaks. Because diagnostic development and validation are time consuming, they should be carried out in anticipation of epidemics rather than in response to them. The diagnostic response to the 2014-15 Ebola epidemic, although ultimately effective, was slow and expensive. If a focused mechanism had existed with the technical and financial resources to drive its development ahead of the outbreak, point-of-care Ebola tests supporting a less costly and more mobile response could have been available early on in the diagnosis process. A new partnering model could drive rapid development of tests and surveillance strategies for novel pathogens that emerge in future outbreaks. We look at lessons learned from the Ebola outbreak and propose specific solutions to improve the speed of new assay development and ensure their effective deployment.
Publisher:
Elsevier
Issue Date:
31-May-2017
URI:
http://hdl.handle.net/10144/618937
DOI:
10.1016/S0140-6736(17)31224-2
PubMed ID:
28577861
Submitted date:
2017-06-12
Language:
en
ISSN:
1474-547X
Appears in Collections:
Other Diseases

Full metadata record

DC FieldValue Language
dc.contributor.authorPerkins, Men
dc.contributor.authorDye, Cen
dc.contributor.authorBalasegaram, Men
dc.contributor.authorBréchot, Cen
dc.contributor.authorMombouli, Jen
dc.contributor.authorRøttingen, Jen
dc.contributor.authorTanner, Men
dc.contributor.authorBoehme, Cen
dc.date.accessioned2017-06-21T14:04:16Z-
dc.date.available2017-06-21T14:04:16Z-
dc.date.issued2017-05-31-
dc.date.submitted2017-06-12-
dc.identifier.citationDiagnostic Preparedness for Infectious Disease Outbreaks. 2017 Lanceten
dc.identifier.issn1474-547X-
dc.identifier.pmid28577861-
dc.identifier.doi10.1016/S0140-6736(17)31224-2-
dc.identifier.urihttp://hdl.handle.net/10144/618937-
dc.description.abstractDiagnostics are crucial in mitigating the effect of disease outbreaks. Because diagnostic development and validation are time consuming, they should be carried out in anticipation of epidemics rather than in response to them. The diagnostic response to the 2014-15 Ebola epidemic, although ultimately effective, was slow and expensive. If a focused mechanism had existed with the technical and financial resources to drive its development ahead of the outbreak, point-of-care Ebola tests supporting a less costly and more mobile response could have been available early on in the diagnosis process. A new partnering model could drive rapid development of tests and surveillance strategies for novel pathogens that emerge in future outbreaks. We look at lessons learned from the Ebola outbreak and propose specific solutions to improve the speed of new assay development and ensure their effective deployment.en
dc.language.isoenen
dc.publisherElsevieren
dc.rightsArchived with thanks to Lancet (London, England)en
dc.titleDiagnostic Preparedness for Infectious Disease Outbreaksen
dc.identifier.journalLanceten

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