Higher risk Sexual Behaviour is associated with Unawareness of HIV-positivity and lack of Viral Suppression - implications for Treatment as Prevention

Hdl Handle:
http://hdl.handle.net/10144/619050
Title:
Higher risk Sexual Behaviour is associated with Unawareness of HIV-positivity and lack of Viral Suppression - implications for Treatment as Prevention
Authors:
Huerga, H; Venables, E; Ben-Farhat, J; van Cutsem, G; Ellman, T; Kenyon, C
Journal:
Scientific Reports
Abstract:
Efficacy of Treatment as Prevention Strategy depends on a variety of factors including individuals' likelihood to test and initiate treatment, viral load and sexual behaviour. We tested the hypothesis that people with higher risk sexual behaviour are less likely to know their HIV-positive status and be virologically suppressed. A cross-sectional population-based survey of individuals aged 15-59 years old was conducted in 2013 in KwaZulu-Natal, South Africa. A two-stage cluster probability sampling was used. After adjustment for age and sex, lack of awareness of HIV-positivity was strongly associated with having more than one sexual partner in the preceding year (aOR: 2.1, 95%CI: 1.5-3.1). Inconsistent condom use was more common in individuals with more than one sexual partner (aOR: 16.6, 95%CI: 7.6-36.7) and those unaware (aOR: 3.7, 95%CI: 2.6-5.4). Among people aware of their HIV-positivity, higher risk sexual behaviour was associated with lack of viral suppression (aOR: 2.2, 95%CI: 1.1-4.5). Risky sexual behaviour seems associated with factors linked to poor health-seeking behaviour which may have negative implications for HIV testing and Treatment as Prevention. Innovative strategies, driven by improved epidemiological and anthropological understanding, are needed to enable comprehensive approaches to HIV prevention.
Publisher:
Nature Publishing Group
Issue Date:
23-Nov-2017
URI:
http://hdl.handle.net/10144/619050
DOI:
10.1038/s41598-017-16382-6
PubMed ID:
29170407
Submitted date:
2017-12-15
Language:
en
ISSN:
2045-2322
Appears in Collections:
HIV/AIDS

Full metadata record

DC FieldValue Language
dc.contributor.authorHuerga, Hen
dc.contributor.authorVenables, Een
dc.contributor.authorBen-Farhat, Jen
dc.contributor.authorvan Cutsem, Gen
dc.contributor.authorEllman, Ten
dc.contributor.authorKenyon, Cen
dc.date.accessioned2017-12-20T23:54:14Z-
dc.date.available2017-12-20T23:54:14Z-
dc.date.issued2017-11-23-
dc.date.submitted2017-12-15-
dc.identifier.citationHigher risk Sexual Behaviour is associated with Unawareness of HIV-positivity and lack of Viral Suppression - implications for Treatment as Prevention. 2017, 7 (1):16117 Sci Repen
dc.identifier.issn2045-2322-
dc.identifier.pmid29170407-
dc.identifier.doi10.1038/s41598-017-16382-6-
dc.identifier.urihttp://hdl.handle.net/10144/619050-
dc.description.abstractEfficacy of Treatment as Prevention Strategy depends on a variety of factors including individuals' likelihood to test and initiate treatment, viral load and sexual behaviour. We tested the hypothesis that people with higher risk sexual behaviour are less likely to know their HIV-positive status and be virologically suppressed. A cross-sectional population-based survey of individuals aged 15-59 years old was conducted in 2013 in KwaZulu-Natal, South Africa. A two-stage cluster probability sampling was used. After adjustment for age and sex, lack of awareness of HIV-positivity was strongly associated with having more than one sexual partner in the preceding year (aOR: 2.1, 95%CI: 1.5-3.1). Inconsistent condom use was more common in individuals with more than one sexual partner (aOR: 16.6, 95%CI: 7.6-36.7) and those unaware (aOR: 3.7, 95%CI: 2.6-5.4). Among people aware of their HIV-positivity, higher risk sexual behaviour was associated with lack of viral suppression (aOR: 2.2, 95%CI: 1.1-4.5). Risky sexual behaviour seems associated with factors linked to poor health-seeking behaviour which may have negative implications for HIV testing and Treatment as Prevention. Innovative strategies, driven by improved epidemiological and anthropological understanding, are needed to enable comprehensive approaches to HIV prevention.en
dc.language.isoenen
dc.publisherNature Publishing Groupen
dc.rightsArchived with thanks to Nature Publishing Group.en
dc.titleHigher risk Sexual Behaviour is associated with Unawareness of HIV-positivity and lack of Viral Suppression - implications for Treatment as Preventionen
dc.identifier.journalScientific Reportsen
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