Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa

Hdl Handle:
http://hdl.handle.net/10144/619061
Title:
Single low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa
Authors:
Taylor, WR; Naw, HK; Maitland, K; Williams, TN; Kapulu, M; D'Alessandro, U; Berkley, JA; Bejon, P; Okebe, J; Achan, J; Amambua, AN; Affara, M; Nwakanma, D; van Geertruyden, JP; Mavoko, M; Lutumba, P; Matangila, J; Brasseur, P; Piola, P; Randremanana, R; Lasry, E; Fanello, C; Onyamboko, M; Schramm, B; Yah, Z; Jones, J; Fairhurst, RM; Diakite, M; Malenga, G; Molyneux, M; Rwagacondo, C; Obonyo, C; Gadisa, E; Aseffa, A; Loolpapit, M; Henry, MC; Dorsey, G; John, C; Sirima, SB; Barnes, KI; Kremsner, P; Day, NP; White, NJ; Mukaka, M
Journal:
BMC Medicine
Abstract:
In 2012, the World Health Organization recommended blocking the transmission of Plasmodium falciparum with single low-dose primaquine (SLDPQ, target dose 0.25 mg base/kg body weight), without testing for glucose-6-phosphate dehydrogenase deficiency (G6PDd), when treating patients with uncomplicated falciparum malaria. We sought to develop an age-based SLDPQ regimen that would be suitable for sub-Saharan Africa.
Publisher:
BioMed Central
Issue Date:
18-Jan-2018
URI:
http://hdl.handle.net/10144/619061
DOI:
10.1186/s12916-017-0990-6
PubMed ID:
29347975
Submitted date:
2018-01-25
Language:
en
ISSN:
1741-7015
Appears in Collections:
Malaria

Full metadata record

DC FieldValue Language
dc.contributor.authorTaylor, WRen
dc.contributor.authorNaw, HKen
dc.contributor.authorMaitland, Ken
dc.contributor.authorWilliams, TNen
dc.contributor.authorKapulu, Men
dc.contributor.authorD'Alessandro, Uen
dc.contributor.authorBerkley, JAen
dc.contributor.authorBejon, Pen
dc.contributor.authorOkebe, Jen
dc.contributor.authorAchan, Jen
dc.contributor.authorAmambua, ANen
dc.contributor.authorAffara, Men
dc.contributor.authorNwakanma, Den
dc.contributor.authorvan Geertruyden, JPen
dc.contributor.authorMavoko, Men
dc.contributor.authorLutumba, Pen
dc.contributor.authorMatangila, Jen
dc.contributor.authorBrasseur, Pen
dc.contributor.authorPiola, Pen
dc.contributor.authorRandremanana, Ren
dc.contributor.authorLasry, Een
dc.contributor.authorFanello, Cen
dc.contributor.authorOnyamboko, Men
dc.contributor.authorSchramm, Ben
dc.contributor.authorYah, Zen
dc.contributor.authorJones, Jen
dc.contributor.authorFairhurst, RMen
dc.contributor.authorDiakite, Men
dc.contributor.authorMalenga, Gen
dc.contributor.authorMolyneux, Men
dc.contributor.authorRwagacondo, Cen
dc.contributor.authorObonyo, Cen
dc.contributor.authorGadisa, Een
dc.contributor.authorAseffa, Aen
dc.contributor.authorLoolpapit, Men
dc.contributor.authorHenry, MCen
dc.contributor.authorDorsey, Gen
dc.contributor.authorJohn, Cen
dc.contributor.authorSirima, SBen
dc.contributor.authorBarnes, KIen
dc.contributor.authorKremsner, Pen
dc.contributor.authorDay, NPen
dc.contributor.authorWhite, NJen
dc.contributor.authorMukaka, Men
dc.date.accessioned2018-01-31T15:41:29Z-
dc.date.available2018-01-31T15:41:29Z-
dc.date.issued2018-01-18-
dc.date.submitted2018-01-25-
dc.identifier.citationSingle low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africa. 2018, 16 (1):11 BMC Meden
dc.identifier.issn1741-7015-
dc.identifier.pmid29347975-
dc.identifier.doi10.1186/s12916-017-0990-6-
dc.identifier.urihttp://hdl.handle.net/10144/619061-
dc.description.abstractIn 2012, the World Health Organization recommended blocking the transmission of Plasmodium falciparum with single low-dose primaquine (SLDPQ, target dose 0.25 mg base/kg body weight), without testing for glucose-6-phosphate dehydrogenase deficiency (G6PDd), when treating patients with uncomplicated falciparum malaria. We sought to develop an age-based SLDPQ regimen that would be suitable for sub-Saharan Africa.en
dc.language.isoenen
dc.publisherBioMed Centralen
dc.rightsArchived with thanks to BMC Medicineen
dc.titleSingle low-dose primaquine for blocking transmission of Plasmodium falciparum malaria - a proposed model-derived age-based regimen for sub-Saharan Africaen
dc.identifier.journalBMC Medicineen

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