Drivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approach

Hdl Handle:
http://hdl.handle.net/10144/619066
Title:
Drivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approach
Authors:
Métras, R; Fournié, G; Dommergues, L; Camacho, A; Cavalerie, L; Mérot, P; Keeling, MJ; Cêtre-Sossah, C; Cardinale, E; Edmunds, WJ
Journal:
PLoS Neglected Tropical Diseases
Abstract:
Rift Valley fever (RVF) is a major zoonotic and arboviral hemorrhagic fever. The conditions leading to RVF epidemics are still unclear, and the relative role of climatic and anthropogenic factors may vary between ecosystems. Here, we estimate the most likely scenario that led to RVF emergence on the island of Mayotte, following the 2006-2007 African epidemic. We developed the first mathematical model for RVF that accounts for climate, animal imports and livestock susceptibility, which is fitted to a 12-years dataset. RVF emergence was found to be triggered by the import of infectious animals, whilst transmissibility was approximated as a linear or exponential function of vegetation density. Model forecasts indicated a very low probability of virus endemicity in 2017, and therefore of re-emergence in a closed system (i.e. without import of infected animals). However, the very high proportion of naive animals reached in 2016 implies that the island remains vulnerable to the import of infectious animals. We recommend reinforcing surveillance in livestock, should RVF be reported is neighbouring territories. Our model should be tested elsewhere, with ecosystem-specific data.
Publisher:
Public Library of Science
Issue Date:
21-Jul-2017
URI:
http://hdl.handle.net/10144/619066
DOI:
10.1371/journal.pntd.0005767
PubMed ID:
28732006
Submitted date:
2018-02-01
Language:
en
ISSN:
1935-2735
Appears in Collections:
Other Diseases

Full metadata record

DC FieldValue Language
dc.contributor.authorMétras, Ren
dc.contributor.authorFournié, Gen
dc.contributor.authorDommergues, Len
dc.contributor.authorCamacho, Aen
dc.contributor.authorCavalerie, Len
dc.contributor.authorMérot, Pen
dc.contributor.authorKeeling, MJen
dc.contributor.authorCêtre-Sossah, Cen
dc.contributor.authorCardinale, Een
dc.contributor.authorEdmunds, WJen
dc.date.accessioned2018-02-06T16:22:25Z-
dc.date.available2018-02-06T16:22:25Z-
dc.date.issued2017-07-21-
dc.date.submitted2018-02-01-
dc.identifier.citationDrivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approach. 2017, 11 (7):e0005767 PLoS Negl Trop Disen
dc.identifier.issn1935-2735-
dc.identifier.pmid28732006-
dc.identifier.doi10.1371/journal.pntd.0005767-
dc.identifier.urihttp://hdl.handle.net/10144/619066-
dc.description.abstractRift Valley fever (RVF) is a major zoonotic and arboviral hemorrhagic fever. The conditions leading to RVF epidemics are still unclear, and the relative role of climatic and anthropogenic factors may vary between ecosystems. Here, we estimate the most likely scenario that led to RVF emergence on the island of Mayotte, following the 2006-2007 African epidemic. We developed the first mathematical model for RVF that accounts for climate, animal imports and livestock susceptibility, which is fitted to a 12-years dataset. RVF emergence was found to be triggered by the import of infectious animals, whilst transmissibility was approximated as a linear or exponential function of vegetation density. Model forecasts indicated a very low probability of virus endemicity in 2017, and therefore of re-emergence in a closed system (i.e. without import of infected animals). However, the very high proportion of naive animals reached in 2016 implies that the island remains vulnerable to the import of infectious animals. We recommend reinforcing surveillance in livestock, should RVF be reported is neighbouring territories. Our model should be tested elsewhere, with ecosystem-specific data.en
dc.language.isoenen
dc.publisherPublic Library of Scienceen
dc.rightsArchived with thanks to PLoS Neglected Tropical Diseasesen
dc.subject.meshAnimalsen
dc.subject.meshBayes Theoremen
dc.subject.meshComorosen
dc.subject.meshEpidemicsen
dc.subject.meshHumansen
dc.subject.meshLivestocken
dc.subject.meshModels, Theoreticalen
dc.subject.meshRift Valley Feveren
dc.subject.meshRift Valley fever virusen
dc.titleDrivers for Rift Valley fever emergence in Mayotte: A Bayesian modelling approachen
dc.identifier.journalPLoS Neglected Tropical Diseasesen

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