Determining sero-prevalence of antibodies against Hepatitis E during an acute outbreak scenario.

Hdl Handle:
http://hdl.handle.net/10144/619225
Title:
Determining sero-prevalence of antibodies against Hepatitis E during an acute outbreak scenario.
Authors:
Lenglet, Annick; Kamau, Charity; Boris, Hogema
Abstract:
OBJECTIVES 3.1 PRIMARY OBJECTIVES To estimate sero prevalence of anti-HEV antibodies (IgG and IgM) in different age groups in Am Timam, Chad 3.2 SECONDARY OBJECTIVES • To determine individual risk factors associated with different anti-HEV antibody status during an acute outbreak; • To determine household level risk factors associated with different anti-HEV antibody status during an acute outbreak; • To compare the sero prevalence of anti-HEV antibodies (IgG and IgM) in different age groups at two different time periods during an acute HEV outbreak to inform our understanding of viral transmission dynamics in a population in this context; • To determine sero prevalence in different age groups of other jaundice causing agents (malaria, hepatitis A, B and C, leptospirosis and arboviral diseases such as yellow fever, viral haemorrhagic fever, Dengue and Rift valley fever; • To compare dried blood spots (DBS) with blood samples for detection of HEV IgM and IgG and HEV RNA through PCR; • To compare oral swabs with blood samples for the detection of HEV IgM and IgG and HEV RNA through PCR.
Affiliation:
MSF-OCA
Issue Date:
Jul-2018
URI:
http://hdl.handle.net/10144/619225
Type:
Other
Language:
en
Description:
Research Protocol
Appears in Collections:
MSF Research Protocols

Full metadata record

DC FieldValue Language
dc.contributor.authorLenglet, Annicken
dc.contributor.authorKamau, Charityen
dc.contributor.authorBoris, Hogemaen
dc.date.accessioned2018-07-27T13:14:16Z-
dc.date.available2018-07-27T13:14:16Z-
dc.date.issued2018-07-
dc.identifier.urihttp://hdl.handle.net/10144/619225-
dc.descriptionResearch Protocolen
dc.description.abstractOBJECTIVES 3.1 PRIMARY OBJECTIVES To estimate sero prevalence of anti-HEV antibodies (IgG and IgM) in different age groups in Am Timam, Chad 3.2 SECONDARY OBJECTIVES • To determine individual risk factors associated with different anti-HEV antibody status during an acute outbreak; • To determine household level risk factors associated with different anti-HEV antibody status during an acute outbreak; • To compare the sero prevalence of anti-HEV antibodies (IgG and IgM) in different age groups at two different time periods during an acute HEV outbreak to inform our understanding of viral transmission dynamics in a population in this context; • To determine sero prevalence in different age groups of other jaundice causing agents (malaria, hepatitis A, B and C, leptospirosis and arboviral diseases such as yellow fever, viral haemorrhagic fever, Dengue and Rift valley fever; • To compare dried blood spots (DBS) with blood samples for detection of HEV IgM and IgG and HEV RNA through PCR; • To compare oral swabs with blood samples for the detection of HEV IgM and IgG and HEV RNA through PCR.en
dc.language.isoenen
dc.rightsThese materials can be used, adapted and copied as long as citation of the source is given including the direct URL to the material. This work is licensed under a Creative Commons Attribution 4.0 International License: http://creativecommons.org/licenses/by/4.0/ https://i.creativecommons.org/l/by/4.0/88x31.pngen
dc.subjectsero-prevalenceen
dc.subjectantibodiesen
dc.subjecthepatitis Een
dc.subjectacute outbreaken
dc.titleDetermining sero-prevalence of antibodies against Hepatitis E during an acute outbreak scenario.en
dc.typeOtheren
dc.contributor.departmentMSF-OCAen
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