Genetic heterogeneity of hepatitis E virus in Darfur, Sudan, and neighboring Chad.

Hdl Handle:
http://hdl.handle.net/10144/66016
Title:
Genetic heterogeneity of hepatitis E virus in Darfur, Sudan, and neighboring Chad.
Authors:
Nicand, E; Armstrong, G L; Enouf, V; Guthmann, J P; Guerin, J P; Caron, M; Nizou, J Y; Andraghetti, R
Journal:
Journal of Medical Virology
Abstract:
The within-outbreak diversity of hepatitis E virus (HEV) was studied during the outbreak of hepatitis E that occurred in Sudan in 2004. Specimens were collected from internally displaced persons living in a Sudanese refugee camp and two camps implanted in Chad. A comparison of the sequences in the ORF2 region of 23 Sudanese isolates and five HEV samples from the two Chadian camps displayed a high similarity (>99.7%) to strains belonging to Genotype 1. But four isolates collected in one of the Chadian camps were close to Genotype 2. Circulation of divergent strains argues for possible multiple sources of infection.
Affiliation:
National Reference Centre for Hepatitis E, Teaching Military Hospital Val de Grâce, Paris, France. en.biol-vdg@filnet.fr
Issue Date:
Dec-2005
URI:
http://hdl.handle.net/10144/66016
DOI:
10.1002/jmv.20487
PubMed ID:
16254969
Type:
Article
Language:
en
ISSN:
0146-6615
Sponsors:
Epicentre
Appears in Collections:
Other Diseases

Full metadata record

DC FieldValue Language
dc.contributor.authorNicand, E-
dc.contributor.authorArmstrong, G L-
dc.contributor.authorEnouf, V-
dc.contributor.authorGuthmann, J P-
dc.contributor.authorGuerin, J P-
dc.contributor.authorCaron, M-
dc.contributor.authorNizou, J Y-
dc.contributor.authorAndraghetti, R-
dc.date.accessioned2009-04-23T14:53:56Z-
dc.date.available2009-04-23T14:53:56Z-
dc.date.issued2005-12-
dc.identifier.citationGenetic heterogeneity of hepatitis E virus in Darfur, Sudan, and neighboring Chad. 2005, 77 (4):519-21 J. Med. Virol.en
dc.identifier.issn0146-6615-
dc.identifier.pmid16254969-
dc.identifier.doi10.1002/jmv.20487-
dc.identifier.urihttp://hdl.handle.net/10144/66016-
dc.description.abstractThe within-outbreak diversity of hepatitis E virus (HEV) was studied during the outbreak of hepatitis E that occurred in Sudan in 2004. Specimens were collected from internally displaced persons living in a Sudanese refugee camp and two camps implanted in Chad. A comparison of the sequences in the ORF2 region of 23 Sudanese isolates and five HEV samples from the two Chadian camps displayed a high similarity (>99.7%) to strains belonging to Genotype 1. But four isolates collected in one of the Chadian camps were close to Genotype 2. Circulation of divergent strains argues for possible multiple sources of infection.en
dc.description.sponsorshipEpicentreen
dc.language.isoenen
dc.rightsArchived with thanks to Journal of Medical Virology and Wiley Publishersen
dc.subject.meshChaden
dc.subject.meshGene Amplificationen
dc.subject.meshGenetic Heterogeneityen
dc.subject.meshGenome, Viralen
dc.subject.meshGenotypeen
dc.subject.meshHepatitis Een
dc.subject.meshHepatitis E virusen
dc.subject.meshHumansen
dc.subject.meshPhylogenyen
dc.subject.meshReverse Transcriptase Polymerase Chain Reactionen
dc.subject.meshSequence Analysisen
dc.subject.meshSudanen
dc.titleGenetic heterogeneity of hepatitis E virus in Darfur, Sudan, and neighboring Chad.en
dc.typeArticleen
dc.contributor.departmentNational Reference Centre for Hepatitis E, Teaching Military Hospital Val de Grâce, Paris, France. en.biol-vdg@filnet.fren
dc.identifier.journalJournal of Medical Virologyen

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