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    Mar 03, 2021
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    Impact of introducing human immunodeficiency virus testing, treatment and care in a tuberculosis clinic in rural Kenya

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    Authors
    Huerga, H
    Spillane, H
    Guerrero, W
    Odongo, A
    Varaine, F
    Affiliation
    Médecins Sans Frontières, Nairobi, Kenya; National Tuberculosis Programme, Homa Bay, Kenya; Médecins Sans Frontières, Paris, France
    Issue Date
    2010-04-09
    Submitted date
    2010-10-08
    
    Metadata
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    Journal
    International Journal of Tuberculosis and Lung Disease
    Abstract
    SETTING: In July 2005, Médecins Sans Frontières and the Ministry of Health, Kenya, implemented an integrated tuberculosis-human immunodeficiency virus (TB-HIV) programme in western Kenya. OBJECTIVE: To evaluate the impact of an integrated TB-HIV programme on patient care and TB programme outcomes. DESIGN: Retrospective evaluation of three time periods: before (January-June 2005), shortly after (January-June 2006) and medium term after (January-December 2007) the implementation of the integrated programme. RESULTS: Respectively 79% and 91% of TB patients were HIV tested shortly and at medium term after service integration. The HIV-positive rate varied from 96% before the intervention to respectively 88% (305/347) and 74% (301/405) after. The estimated number of HIV-positive cases was respectively 303, 323 and 331 in the three periods. The proportion of patients receiving cotrimoxazole prophylaxis increased significantly from 47% (142/303) to 94% (303/323) and 86% (285/331, P < 0.05). Before the intervention, 87% (171/197) of the TB-HIV patients would have been missed when initiating antiretroviral treatment, compared to respectively 29% (60/210) and 36% (78/215) after the integration. The TB programme success rate increased from 56% (230/409) to 71% (319/447) in the third period (P < 0.05); however, there was no significant decrease in the default rate: 20% to 22% (P = 0.66) and 18% (P = 0.37). CONCLUSION: Integrated TB-HIV care has a very positive impact on the management of TB-HIV patients and on TB treatment outcomes.
    URI
    http://hdl.handle.net/10144/114127
    PubMed ID
    20392355
    Additional Links
    http://www.ncbi.nlm.nih.gov/pubmed/20392355
    Type
    Article
    Language
    en
    ISSN
    1815-7920
    Collections
    TB

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