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    Jan 23, 2021
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    Marburg hemorrhagic fever in Durba and Watsa, Democratic Republic of the Congo: clinical documentation, features of illness, and treatment

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    Authors
    Colebunders, Robert
    Tshomba, Antoine
    Van Kerkhove, Maria D
    Bausch, Daniel G
    Campbell, Pat
    Libande, Modeste
    Pirard, Patricia
    Tshioko, Florimond
    Mardel, Simon
    Mulangu, Sabue
    Sleurs, Hilde
    Rollin, Pierre E
    Muyembe-Tamfum, Jean-Jacques
    Jeffs, Benjamin
    Borchert, Matthias
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    Affiliation
    Institute of Tropical Medicine Antwerp, Antwerp, Belgium; University of Antwerp, Antwerp, Belgium; Medecins Sans Frontieres, Brussels, Belgium; Okimo Hospital, Watsa, Democratic Republic of the Congo; Ministry of Health, Kinshasa, Democratic Republic of the Congo; World Health Organization, Kinshasa, Democratic Republic of the Congo; Institut National de Recherche Biomedicale, Kinshasa, Democratic Republic of the Congo; London School of Hygiene and Tropical Medicine, London, United Kingdom; Centers for Disease Control and Prevention, Atlanta, Georgia; Tulane School of Public Health and Tropical Medicine, New Orleans, Louisiana; Medecins Sans Frontieres, Amsterdam, The Netherlands; World Health Organization, Geneva, Switzerland
    Issue Date
    2007-11-15
    
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    Journal
    The Journal of Infectious Diseases
    Abstract
    The objective of the present study was to describe day of onset and duration of symptoms of Marburg hemorrhagic fever (MHF), to summarize the treatments applied, and to assess the quality of clinical documentation. Surveillance and clinical records of 77 patients with MHF cases were reviewed. Initial symptoms included fever, headache, general pain, nausea, vomiting, and anorexia (median day of onset, day 1-2), followed by hemorrhagic manifestations (day 5-8+), and terminal symptoms included confusion, agitation, coma, anuria, and shock. Treatment in isolation wards was acceptable, but the quality of clinical documentation was unsatisfactory. Improved clinical documentation is necessary for a basic evaluation of supportive treatment.
    URI
    http://hdl.handle.net/10144/116349
    DOI
    10.1086/520543
    PubMed ID
    17940943
    Additional Links
    http://www.journals.uchicago.edu/doi/abs/10.1086/520543?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmed
    Type
    Article
    Language
    en
    ISSN
    0022-1899
    ae974a485f413a2113503eed53cd6c53
    10.1086/520543
    Scopus Count
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