Marburg hemorrhagic fever in Durba and Watsa, Democratic Republic of the Congo: clinical documentation, features of illness, and treatment
Authors
Colebunders, RobertTshomba, Antoine
Van Kerkhove, Maria D
Bausch, Daniel G
Campbell, Pat
Libande, Modeste
Pirard, Patricia
Tshioko, Florimond
Mardel, Simon
Mulangu, Sabue
Sleurs, Hilde
Rollin, Pierre E
Muyembe-Tamfum, Jean-Jacques
Jeffs, Benjamin
Borchert, Matthias
Affiliation
Institute of Tropical Medicine Antwerp, Antwerp, Belgium; University of Antwerp, Antwerp, Belgium; Medecins Sans Frontieres, Brussels, Belgium; Okimo Hospital, Watsa, Democratic Republic of the Congo; Ministry of Health, Kinshasa, Democratic Republic of the Congo; World Health Organization, Kinshasa, Democratic Republic of the Congo; Institut National de Recherche Biomedicale, Kinshasa, Democratic Republic of the Congo; London School of Hygiene and Tropical Medicine, London, United Kingdom; Centers for Disease Control and Prevention, Atlanta, Georgia; Tulane School of Public Health and Tropical Medicine, New Orleans, Louisiana; Medecins Sans Frontieres, Amsterdam, The Netherlands; World Health Organization, Geneva, SwitzerlandIssue Date
2007-11-15
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The objective of the present study was to describe day of onset and duration of symptoms of Marburg hemorrhagic fever (MHF), to summarize the treatments applied, and to assess the quality of clinical documentation. Surveillance and clinical records of 77 patients with MHF cases were reviewed. Initial symptoms included fever, headache, general pain, nausea, vomiting, and anorexia (median day of onset, day 1-2), followed by hemorrhagic manifestations (day 5-8+), and terminal symptoms included confusion, agitation, coma, anuria, and shock. Treatment in isolation wards was acceptable, but the quality of clinical documentation was unsatisfactory. Improved clinical documentation is necessary for a basic evaluation of supportive treatment.DOI
10.1086/520543PubMed ID
17940943Additional Links
http://www.journals.uchicago.edu/doi/abs/10.1086/520543?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%3dpubmedType
ArticleLanguage
enISSN
0022-1899ae974a485f413a2113503eed53cd6c53
10.1086/520543
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