Wondje, Christelle Mbondji
AffiliationLaboratoire d'Epidémiologie et de Santé Publique, Centre Pasteur du Cameroun, Yaoundé, Cameroon; Unite´ d’Epide´miologie des Maladies Emergentes, Institut Pasteur, Paris, France; Laboratoire des Mycobacte´ ries, Centre Pasteur du Cameroun, Yaounde , Cameroon; Mycobacterium Unit, Institute of Tropical Medecine, Antwerp, Belgium; Hopital de District d’Akonolinga, Ministere de la Sante Publique, Yaounde, Cameroon; Medecins Sans Frontieres-Suisse, Yaounde, Cameroon; Groupe d’Etude des Interactions Hotes Parasites, Universite d Angers, Angers, France; Equipe Avenir Institut National de la Sante´ et de la Recherche Me´ dicale, Institut Pasteur Korea, Seongbuk-gu, Seoul, Korea
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JournalPLoS Neglected Tropical Diseases
AbstractBACKGROUND: Buruli ulcer is an infectious disease involving the skin, caused by Mycobacterium ulcerans. This disease is associated with areas where the water is slow-flowing or stagnant. However, the exact mechanism of transmission of the bacillus and the development of the disease through human activities is unknown. METHODOLOGY/PRINCIPAL FINDINGS: A case-control study to identify Buruli ulcer risk factors in Cameroon compared case-patients with community-matched controls on one hand and family-matched controls on the other hand. Risk factors identified by the community-matched study (including 163 pairs) were: having a low level of education, swamp wading, wearing short, lower-body clothing while farming, living near a cocoa plantation or woods, using adhesive bandages when hurt, and using mosquito coils. Protective factors were: using bed nets, washing clothes, and using leaves as traditional treatment or rubbing alcohol when hurt. The family-matched study (including 118 pairs) corroborated the significance of education level, use of bed nets, and treatment with leaves. CONCLUSIONS/SIGNIFICANCE: Covering limbs during farming activities is confirmed as a protective factor guarding against Buruli ulcer disease, but newly identified factors including wound treatment and use of bed nets may provide new insight into the unknown mode of transmission of M. ulcerans or the development of the disease.
- Adequate wound care and use of bed nets as protective factors against Buruli Ulcer: results from a case control study in Cameroon.
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- Issue date: 2011 Nov
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- Authors: Raghunathan PL, Whitney EA, Asamoa K, Stienstra Y, Taylor TH Jr, Amofah GK, Ofori-Adjei D, Dobos K, Guarner J, Martin S, Pathak S, Klutse E, Etuaful S, van der Graaf WT, van der Werf TS, King CH, Tappero JW, Ashford DA
- Issue date: 2005 May 15
- Environmental and health-related risk factors for Mycobacterium ulcerans disease (Buruli ulcer) in Benin.
- Authors: Nackers F, Johnson RC, Glynn JR, Zinsou C, Tonglet R, Portaels F
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- Issue date: 2009 Jun 23
- Risk factors for buruli ulcer in Ghana-a case control study in the Suhum-Kraboa-Coaltar and Akuapem South Districts of the eastern region.
- Authors: Kenu E, Nyarko KM, Seefeld L, Ganu V, Käser M, Lartey M, Calys-Tagoe BN, Koram K, Adanu R, Razum O, Afari E, Binka FN
- Issue date: 2014