• A Worldwide Map of Plasmodium Falciparum K13-Propeller Polymorphisms

      Ménard, D; Khim, N; Beghain, J; Adegnika, AA; Shafiul-Alam, M; Amodu, O; Rahim-Awab, G; Barnadas, C; Berry, A; Boum, Y; et al. (Massachusetts Medical Society, 2016-06-23)
      Recent gains in reducing the global burden of malaria are threatened by the emergence of Plasmodium falciparum resistance to artemisinins. The discovery that mutations in portions of a P. falciparum gene encoding kelch (K13)-propeller domains are the major determinant of resistance has provided opportunities for monitoring such resistance on a global scale.