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    Browsing Malaria by Authors 
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    • Malaria
    • Browsing Malaria by Authors
    •   Home
    • 1 Published Research and Commentary
    • Malaria
    • Browsing Malaria by Authors
    Dec 07, 2019
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    Browsing Malaria by Authors

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        Selection of Plasmodium Falciparum pfcrt and pfmdr1 Polymorphisms After Treatment with Artesunate-Amodiaquine Fixed Dose Combination or Artemether-Lumefantrine in Liberia

        Otienoburu, SD; Maïga-Ascofaré, O; Schramm, B; Jullien, V; Jones, JJ; Zolia, YM; Houzé, P; Ashley, EA; Kiechel, JR; Guérin, PJ; et al. (BioMed Central (Springer Science), 2016-09-05)
        Plasmodium falciparum uncomplicated malaria can successfully be treated with an artemisinin-based combination therapy (ACT). However resistance is spreading to the different ACT compounds; the artemisinin derivative and the partner drug. Studies of P. falciparum polymorphisms associated with drug resistance can provide a useful tool to track resistance and guide treatment policy as well as an in-depth understanding of the development and spread of resistance.
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