Switching to second-line antiretroviral therapy in resource-limited settings: comparison of programmes with and without viral load monitoring.
Brinkhof, Martin W G
AffiliationInstitute of Social and Preventive Medicine (ISPM), University of Bern, Bern, Switzerland.
MetadataShow full item record
JournalAIDS (London, England)
AbstractIn high-income countries, viral load is routinely measured to detect failure of antiretroviral therapy (ART) and guide switching to second-line ART. Viral load monitoring is not generally available in resource-limited settings. We examined switching from nonnucleoside reverse transcriptase inhibitor (NNRTI)-based first-line regimens to protease inhibitor-based regimens in Africa, South America and Asia.