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dc.contributor.authorHailu, Asrat
dc.contributor.authorMusa, Ahmed
dc.contributor.authorWasunna, Monique
dc.contributor.authorBalasegaram, Manica
dc.contributor.authorYifru, Sisay
dc.contributor.authorMengistu, Getahun
dc.contributor.authorHurissa, Zewdu
dc.contributor.authorHailu, Workagegnehu
dc.contributor.authorWeldegebreal, Teklu
dc.contributor.authorTesfaye, Samson
dc.contributor.authorMakonnen, Eyasu
dc.contributor.authorKhalil, Eltahir
dc.contributor.authorAhmed, Osama
dc.contributor.authorFadlalla, Ahmed
dc.contributor.authorEl-Hassan, Ahmed
dc.contributor.authorRaheem, Muzamil
dc.contributor.authorMueller, Marius
dc.contributor.authorKoummuki, Yousif
dc.contributor.authorRashid, Juma
dc.contributor.authorMbui, Jane
dc.contributor.authorMucee, Geoffrey
dc.contributor.authorNjoroge, Simon
dc.contributor.authorManduku, Veronica
dc.contributor.authorMusibi, Alice
dc.contributor.authorMutuma, Geoffrey
dc.contributor.authorKirui, Fredrick
dc.contributor.authorLodenyo, Hudson
dc.contributor.authorMutea, Dedan
dc.contributor.authorKirigi, George
dc.contributor.authorEdwards, Tansy
dc.contributor.authorSmith, Peter
dc.contributor.authorMuthami, Lawrence
dc.contributor.authorRoyce, Catherine
dc.contributor.authorEllis, Sally
dc.contributor.authorAlobo, Moses
dc.contributor.authorOmollo, Raymond
dc.contributor.authorKesusu, Josephine
dc.contributor.authorOwiti, Rhoda
dc.contributor.authorKinuthia, John
dc.date.accessioned2011-04-06T21:26:14Z
dc.date.available2011-04-06T21:26:14Z
dc.date.issued2010-10-26
dc.date.submitted2011-03-10
dc.identifier.citationPLoS Negl Trop Dis 2010;4(10):e709en
dc.identifier.issn1935-2735
dc.identifier.pmid21049059
dc.identifier.doi10.1371/journal.pntd.0000709
dc.identifier.urihttp://hdl.handle.net/10144/127587
dc.description.abstractVisceral leishmaniasis (VL) is a major health problem in developing countries. The untreated disease is fatal, available treatment is expensive and often toxic, and drug resistance is increasing. Improved treatment options are needed. Paromomycin was shown to be an efficacious first-line treatment with low toxicity in India.
dc.language.isoenen
dc.relation.urlhttp://www.plosntds.org/article/info%3Adoi%2F10.1371%2Fjournal.pntd.0000709en
dc.rightsArchived with thanks to PLoS Neglected Tropical Diseasesen
dc.subject.meshAdolescenten
dc.subject.meshAdulten
dc.subject.meshAfrica, Easternen
dc.subject.meshAntiprotozoal Agentsen
dc.subject.meshChilden
dc.subject.meshChild, Preschoolen
dc.subject.meshFemaleen
dc.subject.meshGeographyen
dc.subject.meshHumansen
dc.subject.meshLeishmania donovanien
dc.subject.meshLeishmaniasis, Visceralen
dc.subject.meshMaleen
dc.subject.meshMiddle Ageden
dc.subject.meshParomomycinen
dc.subject.meshTreatment Outcomeen
dc.subject.meshYoung Adulten
dc.titleGeographical Variation in the Response of Visceral Leishmaniasis to Paromomycin in East Africa: A Multicentre, Open-Label, Randomized Trialen
dc.typeArticleen
dc.contributor.departmentAddis Ababa University, Ethiopia; Institute of Endemic Diseases, University of Khartoum, Sudan; Centre for Clinical Research, Kenya Medical Research Institute, Kenya; Medecins Sans Frontieres, Amsterdam; Drugs for Neglected Diseases initiative (DNDi), Switzerland; Gondar University, Ethiopia; Arba Minch Hospital, Regional Health Bureau of SNNP state, Ethiopia; Faculty of Medicine, Gedaref University, Sudan; London School of Hygiene and Tropical Medicine, United Kingdomen
dc.identifier.journalPLoS Neglected Tropical Diseasesen
refterms.dateFOA2019-03-04T08:40:24Z
html.description.abstractVisceral leishmaniasis (VL) is a major health problem in developing countries. The untreated disease is fatal, available treatment is expensive and often toxic, and drug resistance is increasing. Improved treatment options are needed. Paromomycin was shown to be an efficacious first-line treatment with low toxicity in India.


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