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    Jan 20, 2021
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    Demographic characteristics and opportunistic diseases associated with attrition during preparation for antiretroviral therapy in primary health centres in Kibera, Kenya.

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    Name:
    Tayler-Smith Attrition pre ART ...
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    Authors
    Tayler-Smith, K
    Zachariah, R
    Manzi, M
    Kizito, W
    Vandenbulcke, A
    Dunkley, S
    von Rege, D
    Reid, T
    Arnould, L
    Suleh, A
    Harries, A D
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    Affiliation
    Medecins sans Frontieres, Medical Department (Operational Research), Brussels Operational Center, Luxembourg, Luxembourg.
    Issue Date
    2011-05
    
    Metadata
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    Journal
    Tropical Medicine & International Health : TM & IH
    Abstract
    Using routine data from HIV-positive adult patients eligible for antiretroviral therapy (ART), we report on routinely collected demographic characteristics and opportunistic diseases associated with pre-ART attrition (deaths and loss to follow-up). Among 2471 ART eligible patients, enrolled between January 2005 and November 2008, 446 (18%) were lost to attrition pre-ART. Adjusted risk factors significantly associated with pre-ART attrition included age <35 years (Odds Ratio, OR 1.4, 95% Confidence Interval, CI 1.1-1.8), severe malnutrition (OR 1.5, 95% CI 1.1-2.0), active pulmonary tuberculosis (OR 1.6, 95% CI 1.1-2.4), severe bacterial infections including severe bacterial pneumonia (OR 1.9, 95% CI 1.2-2.8) and prolonged unexplained fever (>1 month), (OR 2.6, 95% CI 1.3-5.2). This study highlights a number of clinical markers associated with pre-ART attrition that could serve as 'pointers' or screening tools to identify patients who merit fast-tracking onto ART and/or closer clinical attention and follow-up.
    URI
    http://hdl.handle.net/10144/132527
    DOI
    10.1111/j.1365-3156.2011.02740.x
    PubMed ID
    21306485
    Language
    en
    ISSN
    1365-3156
    ae974a485f413a2113503eed53cd6c53
    10.1111/j.1365-3156.2011.02740.x
    Scopus Count
    Collections
    HIV/AIDS

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