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dc.contributor.authorTayler-Smith, K*
dc.contributor.authorZachariah, R*
dc.contributor.authorManzi, M*
dc.contributor.authorKizito, W*
dc.contributor.authorVandenbulcke, A*
dc.contributor.authorDunkley, S*
dc.contributor.authorvon Rege, D*
dc.contributor.authorReid, T*
dc.contributor.authorArnould, L*
dc.contributor.authorSuleh, A*
dc.contributor.authorHarries, A D*
dc.date.accessioned2011-06-02T14:56:32Z
dc.date.available2011-06-02T14:56:32Z
dc.date.issued2011-05
dc.identifier.citationDemographic characteristics and opportunistic diseases associated with attrition during preparation for antiretroviral therapy in primary health centres in Kibera, Kenya. 2011, 16 (5):579-84 Trop. Med. Int. Healthen
dc.identifier.issn1365-3156
dc.identifier.pmid21306485
dc.identifier.doi10.1111/j.1365-3156.2011.02740.x
dc.identifier.urihttp://hdl.handle.net/10144/132527
dc.description.abstractUsing routine data from HIV-positive adult patients eligible for antiretroviral therapy (ART), we report on routinely collected demographic characteristics and opportunistic diseases associated with pre-ART attrition (deaths and loss to follow-up). Among 2471 ART eligible patients, enrolled between January 2005 and November 2008, 446 (18%) were lost to attrition pre-ART. Adjusted risk factors significantly associated with pre-ART attrition included age <35 years (Odds Ratio, OR 1.4, 95% Confidence Interval, CI 1.1-1.8), severe malnutrition (OR 1.5, 95% CI 1.1-2.0), active pulmonary tuberculosis (OR 1.6, 95% CI 1.1-2.4), severe bacterial infections including severe bacterial pneumonia (OR 1.9, 95% CI 1.2-2.8) and prolonged unexplained fever (>1 month), (OR 2.6, 95% CI 1.3-5.2). This study highlights a number of clinical markers associated with pre-ART attrition that could serve as 'pointers' or screening tools to identify patients who merit fast-tracking onto ART and/or closer clinical attention and follow-up.
dc.language.isoenen
dc.rightsArchived on this site with the kind permission of Wiley-Blackwell, [url]http://www.blackwell-synergy.com/loi/tmi[/url]en
dc.titleDemographic characteristics and opportunistic diseases associated with attrition during preparation for antiretroviral therapy in primary health centres in Kibera, Kenya.en
dc.contributor.departmentMedecins sans Frontieres, Medical Department (Operational Research), Brussels Operational Center, Luxembourg, Luxembourg.en
dc.identifier.journalTropical Medicine & International Health : TM & IHen
refterms.dateFOA2019-03-04T08:45:58Z
html.description.abstractUsing routine data from HIV-positive adult patients eligible for antiretroviral therapy (ART), we report on routinely collected demographic characteristics and opportunistic diseases associated with pre-ART attrition (deaths and loss to follow-up). Among 2471 ART eligible patients, enrolled between January 2005 and November 2008, 446 (18%) were lost to attrition pre-ART. Adjusted risk factors significantly associated with pre-ART attrition included age <35 years (Odds Ratio, OR 1.4, 95% Confidence Interval, CI 1.1-1.8), severe malnutrition (OR 1.5, 95% CI 1.1-2.0), active pulmonary tuberculosis (OR 1.6, 95% CI 1.1-2.4), severe bacterial infections including severe bacterial pneumonia (OR 1.9, 95% CI 1.2-2.8) and prolonged unexplained fever (>1 month), (OR 2.6, 95% CI 1.3-5.2). This study highlights a number of clinical markers associated with pre-ART attrition that could serve as 'pointers' or screening tools to identify patients who merit fast-tracking onto ART and/or closer clinical attention and follow-up.


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