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    Apr 18, 2021
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    Operational challenges in managing Isoniazid Preventive Therapy in child contacts: A high-burden setting perspective.

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    Authors
    van Wyk, S S
    Reid, A J
    Mandalakas, A M
    Enarson, D A
    Beyers, N
    Morrison, J
    Hesseling, A C
    Issue Date
    2011-07-08
    
    Metadata
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    Journal
    BMC Public Health
    Abstract
    ABSTRACT: BACKGROUND: The study was conducted at a high TB-HIV burden primary health community clinic in Cape Town, South Africa. We describe the management of children under five years of age in household contact with a smear and/or culture-positive adult TB case. METHODS: This study was a record review of routinely-collected programme data. RESULTS: A total of 1094 adult TB case folders were reviewed. From all identified contacts, 149 children should have received IPT based on local guidelines; in only 2/149 IPT was initiated. Management of child contacts of sputum smear and/or culture-positive compared to sputum-negative TB patients were similar. CONCLUSIONS: IPT delivery to children remains an operational challenge, especially in high TB-HIV burden communities. A tool to improve IPT management and targeting sputum smear and/or culture-positive TB child contacts may overcome some of these challenges and should be developed and piloted in such settings.
    URI
    http://hdl.handle.net/10144/138469
    DOI
    10.1186/1471-2458-11-544
    PubMed ID
    21740580
    Language
    en
    ISSN
    1471-2458
    ae974a485f413a2113503eed53cd6c53
    10.1186/1471-2458-11-544
    Scopus Count
    Collections
    TB

    entitlement

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