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dc.contributor.authorvan Wyk, S S
dc.contributor.authorReid, A J
dc.contributor.authorMandalakas, A M
dc.contributor.authorEnarson, D A
dc.contributor.authorBeyers, N
dc.contributor.authorMorrison, J
dc.contributor.authorHesseling, A C
dc.date.accessioned2011-07-30T16:56:34Z
dc.date.available2011-07-30T16:56:34Z
dc.date.issued2011-07-08
dc.identifier.citationOperational challenges in managing Isoniazid Preventive Therapy in child contacts: A high-burden setting perspective. 2011, 11 (1):544notBMC Public Healthen
dc.identifier.issn1471-2458
dc.identifier.pmid21740580
dc.identifier.doi10.1186/1471-2458-11-544
dc.identifier.urihttp://hdl.handle.net/10144/138469
dc.description.abstractABSTRACT: BACKGROUND: The study was conducted at a high TB-HIV burden primary health community clinic in Cape Town, South Africa. We describe the management of children under five years of age in household contact with a smear and/or culture-positive adult TB case. METHODS: This study was a record review of routinely-collected programme data. RESULTS: A total of 1094 adult TB case folders were reviewed. From all identified contacts, 149 children should have received IPT based on local guidelines; in only 2/149 IPT was initiated. Management of child contacts of sputum smear and/or culture-positive compared to sputum-negative TB patients were similar. CONCLUSIONS: IPT delivery to children remains an operational challenge, especially in high TB-HIV burden communities. A tool to improve IPT management and targeting sputum smear and/or culture-positive TB child contacts may overcome some of these challenges and should be developed and piloted in such settings.
dc.languageENG
dc.language.isoenen
dc.rightsArchived via Open Access and with thanks to BMC Public Healthen
dc.titleOperational challenges in managing Isoniazid Preventive Therapy in child contacts: A high-burden setting perspective.en
dc.identifier.journalBMC Public Healthen
refterms.dateFOA2019-03-04T08:47:04Z
html.description.abstractABSTRACT: BACKGROUND: The study was conducted at a high TB-HIV burden primary health community clinic in Cape Town, South Africa. We describe the management of children under five years of age in household contact with a smear and/or culture-positive adult TB case. METHODS: This study was a record review of routinely-collected programme data. RESULTS: A total of 1094 adult TB case folders were reviewed. From all identified contacts, 149 children should have received IPT based on local guidelines; in only 2/149 IPT was initiated. Management of child contacts of sputum smear and/or culture-positive compared to sputum-negative TB patients were similar. CONCLUSIONS: IPT delivery to children remains an operational challenge, especially in high TB-HIV burden communities. A tool to improve IPT management and targeting sputum smear and/or culture-positive TB child contacts may overcome some of these challenges and should be developed and piloted in such settings.


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