• Login
    View Item 
    •   Home
    • 1 Published Research and Commentary
    • Other Diseases
    • View Item
    •   Home
    • 1 Published Research and Commentary
    • Other Diseases
    • View Item
    Jan 26, 2021
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of MSFTitleAuthorsSubjectsPublisherJournalThis CollectionTitleAuthorsSubjectsPublisherJournal

    Shigella dysenteriae serotype 1 in west Africa: intervention strategy for an outbreak in Sierra Leone.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    lancet guerin 2003 shigella.pdf
    Size:
    118.0Kb
    Format:
    PDF
    Download
    Authors
    Guerin, P J
    Brasher, C
    Baron, E
    Mic, D
    Grimont, F
    Ryan, M
    Aavitsland, P
    Legros, D
    Affiliation
    Division of Infectious Disease Control, Norwegian Institute of Public Health, Oslo, Norway. philippe.guerin@epicentre.msf.org
    Issue Date
    2003-08-30
    
    Metadata
    Show full item record
    Journal
    Lancet
    Abstract
    In November 1999, a Médecins Sans Frontières team based in the southeastern part of Sierra Leone reported an increased number of cases of bloody diarrhoea. Shigella dysenteriae serotype 1 (Sd1) was isolated in the early cases. A total of 4218 cases of dysentery were reported in Kenema district from December, 1999, to March, 2000. The overall attack rate was 7.5%. The attack rate was higher among children younger than 5 years than in the rest of the population (11.2% vs 6.8%; relative risk=1.6; 95% CI 1.5-1.8). The case fatality was 3.1%, also higher for children younger than 5 years (6.1% vs 2.1%; relative risk=2.9; 95% CI 2.1-4.1]). Among 583 patients regarded at increased risk of death who were treated with ciprofloxacin in isolation centres, case fatality was 0.9%. A 5-day ciprofloxacin regimen, targeted to the most severe cases of bloody diarrhoea, was highly effective. This is the first time a large outbreak caused by Sd1 has been reported in west Africa.
    Publisher
    Elsevier
    URI
    http://hdl.handle.net/10144/18240
    PubMed ID
    12957094
    Additional Links
    http://www.thelancet.com
    Language
    en
    ISSN
    1474-547X
    Collections
    Other Diseases

    entitlement

    Related articles

    • Case management of a multidrug-resistant Shigella dysenteriae serotype 1 outbreak in a crisis context in Sierra Leone, 1999-2000.
    • Authors: Guerin PJ, Brasher C, Baron E, Mic D, Grimont F, Ryan M, Aavitsland P, Legros D
    • Issue date: 2004 Nov
    • [Ciprofloxacin in the treatment of dysentery caused by type 1 Shigella dysenteriae during an epidemic in Rwandan refugees in Goma in 1994].
    • Authors: Laureillard D, Paquet C, Malvy D
    • Issue date: 1998 Jul-Aug
    • [An outbreak of Shigella dysenteriae type 1 dysentery in a refugee camp in Rwanda].
    • Authors: Paquet C, Leborgne P, Sasse A, Varaine F
    • Issue date: 1995 May-Jun
    • Emergence of nalidixic acid resistant Shigella dysenteriae type 1 in Thailand: an outbreak associated with consumption of a coconut milk dessert.
    • Authors: Hoge CW, Bodhidatta L, Tungtaem C, Echeverria P
    • Issue date: 1995 Dec
    • Nonserotypeable Shigella dysenteriae isolated from a Dutch patient returning from India.
    • Authors: Kuijper EJ, van Eeden A, de Wever B, van Ketel R, Dankert J
    • Issue date: 1997 Jul
    DSpace software (copyright © 2002 - 2021)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.