Treatment Outcomes Stratified by Baseline Immunological Status Among Young Children Receiving Nonnucleoside Reverse-Transcriptase Inhibitor-Based Antiretroviral Therapy in Resource-Limited Settings.
Authors
O'Brien, D PSauvageot, D
Olson, D
Schaeffer, M
Humblet, P
Pudjades, M
Ellman, T
Zachariah, R
Szumilin, E
Arnould, L
Reid, T
Affiliation
AIDS Working Group, Médecins Sans Frontières, Paris, France. daniel.obrien@amsterdam.msf.orgIssue Date
2007-05-01
Metadata
Show full item recordJournal
Clinical Infectious DiseasesAbstract
A study of 568 children aged <5 years who commenced nonnucleoside reverse-transcriptase inhibitor-based antiretroviral therapy in resource-limited settings revealed good early outcomes. After 12 months of antiretroviral therapy, survival probability was 0.89 (95% confidence interval, 0.86-0.92), with no significant difference among children stratified on the basis of baseline immunological levels; 62% attained a CD4 cell percentage >25%, and 7% continued to have a CD4 cell percentage <15%.DOI
10.1086/513433PubMed ID
17407046Additional Links
http://www.journals.uchicago.edu/page/cid/brief.htmlLanguage
enISSN
1537-6591ae974a485f413a2113503eed53cd6c53
10.1086/513433