Show simple item record

dc.contributor.authorBabiker, Z O E
dc.contributor.authorDavidson, R N N
dc.contributor.authorMazinda, C
dc.contributor.authorKipngetich, S
dc.contributor.authorRitmeijer, K
dc.date.accessioned2008-02-14T11:36:19Z
dc.date.available2008-02-14T11:36:19Z
dc.date.issued2007-04
dc.identifier.citationUtility of lymph node aspiration in the diagnosis of visceral leishmaniasis in Sudan. 2007, 76 (4):689-93 Am. J. Trop. Med. Hyg.en
dc.identifier.issn0002-9637
dc.identifier.pmid17426171
dc.identifier.urihttp://hdl.handle.net/10144/18275
dc.description.abstractWe evaluated lymph node aspiration (LNA) as a simple diagnostic procedure for visceral leishmaniasis (VL). Lymph node aspiration was compared with the direct agglutination test (DAT) using a diagnostic titer > or = 1:6,400 in 7,880 suspected VL patients in eastern Sudan. Compared with DAT, LNA had a sensitivity of 65.1% (95% confidence interval = 63.5-66.6%). Parasite density in LNA correlated strongly with DAT titers (P < 0.0001), and low parasite density accounted for 78.1% of positive LNA results with DAT titers < 1:6,400 (n = 782). Risk factors predictive of a positive LNA result were an age of 1-29 years, male sex, a hemoglobin level < 10.0 g/dL, a DAT titer > or = 1:800, and a location with a higher prevalence of VL. Lymph node and splenic aspirations were similarly accurate as tests of cure after treatment of 50 VL patients in southern Sudan. Pre-treatment LNA results were negative in 20 cases of severe post kala-azar dermal leishmaniasis.
dc.language.isoenen
dc.publisherPublished by: American Society of Tropical Medicine and Hygiene
dc.relation.urlhttp://www.ajtmh.org
dc.rightsArchived on this site with the kind permission of the American Society of Tropical Medicine and Hygiene,www.astmh.orgen
dc.subject.meshAdolescenten
dc.subject.meshAdulten
dc.subject.meshAgglutination Testsen
dc.subject.meshAntimony Sodium Gluconateen
dc.subject.meshAntiprotozoal Agentsen
dc.subject.meshBiopsy, Needleen
dc.subject.meshChilden
dc.subject.meshChild, Preschoolen
dc.subject.meshFemaleen
dc.subject.meshHumansen
dc.subject.meshInfanten
dc.subject.meshLeishmaniasis, Visceralen
dc.subject.meshLymph Nodesen
dc.subject.meshMaleen
dc.subject.meshSeasonsen
dc.subject.meshSensitivity and Specificityen
dc.subject.meshSudanen
dc.titleUtility of Lymph Node Aspiration in the Diagnosis of Visceral Leishmaniasis in Sudan.en
dc.contributor.departmentMédecins Sans Frontières-Holland, Amsterdam, The Netherlands. zahir_babiker@yahoo.co.uken
dc.identifier.journalThe American Journal of Tropical Medicine and Hygieneen
refterms.dateFOA2019-03-04T09:20:17Z
html.description.abstractWe evaluated lymph node aspiration (LNA) as a simple diagnostic procedure for visceral leishmaniasis (VL). Lymph node aspiration was compared with the direct agglutination test (DAT) using a diagnostic titer > or = 1:6,400 in 7,880 suspected VL patients in eastern Sudan. Compared with DAT, LNA had a sensitivity of 65.1% (95% confidence interval = 63.5-66.6%). Parasite density in LNA correlated strongly with DAT titers (P < 0.0001), and low parasite density accounted for 78.1% of positive LNA results with DAT titers < 1:6,400 (n = 782). Risk factors predictive of a positive LNA result were an age of 1-29 years, male sex, a hemoglobin level < 10.0 g/dL, a DAT titer > or = 1:800, and a location with a higher prevalence of VL. Lymph node and splenic aspirations were similarly accurate as tests of cure after treatment of 50 VL patients in southern Sudan. Pre-treatment LNA results were negative in 20 cases of severe post kala-azar dermal leishmaniasis.


Files in this item

Thumbnail
Name:
Am J Babiker.pdf
Size:
133.4Kb
Format:
PDF

This item appears in the following Collection(s)

Show simple item record