• Login
    View Item 
    •   Home
    • 1 Published Research and Commentary
    • TB
    • View Item
    •   Home
    • 1 Published Research and Commentary
    • TB
    • View Item
    Jan 19, 2021
    JavaScript is disabled for your browser. Some features of this site may not work without it.

    Browse

    All of MSFTitleAuthorsSubjectsPublisherJournalThis CollectionTitleAuthorsSubjectsPublisherJournal

    WHO Clinical Staging of HIV Infection and Disease, Tuberculosis and Eligibility for Antiretroviral Treatment: Relationship to CD4 Lymphocyte Counts.

    • CSV
    • RefMan
    • EndNote
    • BibTex
    • RefWorks
    Thumbnail
    Name:
    tb 2 teck who.pdf
    Size:
    114.8Kb
    Format:
    PDF
    Download
    Authors
    Teck, R
    Ascurra, O
    Gomani, P
    Manzi, M
    Pasulani, O
    Kusamale, J
    Salaniponi, F M L
    Humblet, P
    Nunn, P
    Scano, F
    Harries, A D
    Zachariah, R
    Show allShow less
    Affiliation
    Médecins sans Frontières-Luxembourg, Thyolo, Malawi.
    Issue Date
    2005-03
    
    Metadata
    Show full item record
    Journal
    International Journal of Tuberculosis and Lung Disease
    Abstract
    SETTING: Thyolo district, Malawi. OBJECTIVES: To determine in HIV-positive individuals aged over 13 years CD4 lymphocyte counts in patients classified as WHO Clinical Stage III and IV and patients with active and previous tuberculosis (TB). DESIGN: Cross-sectional study. METHODS: CD4 lymphocyte counts were determined in all consecutive HIV-positive individuals presenting to the antiretroviral clinic in WHO Stage III and IV. RESULTS: A CD4 lymphocyte count of < or = 350 cells/microl was found in 413 (90%) of 457 individuals in WHO Stage III and IV, 96% of 77 individuals with active TB, 92% of 65 individuals with a history of pulmonary TB (PTB) in the last year, 91% of 89 individuals with a previous history of PTB beyond 1 year, 81% of 32 individuals with a previous history of extra-pulmonary TB, 93% of 107 individuals with active or past TB with another HIV-related disease and 89% of 158 individuals with active or past TB without another HIV-related disease. CONCLUSIONS: In our setting, nine of 10 HIV-positive individuals presenting in WHO Stage III and IV and with active or previous TB have CD4 counts of < or = 350 cells/microl. It would thus be reasonable, in this or similar settings where CD4 counts are unavailable for clinical management, for all such patients to be considered eligible for antiretroviral therapy.
    Publisher
    International Union Against TB and Lung Disease
    URI
    http://hdl.handle.net/10144/18292
    PubMed ID
    15786887
    Additional Links
    http://www.ingentaconnect.com/content/iuatld/ijtld
    Language
    en
    ISSN
    1027-3719
    Collections
    TB

    entitlement

    Related articles

    • CD4 validation for the World Health Organization classification and clinical staging of HIV/AIDS in a developing country.
    • Authors: Edathodu J, Ali B, Alrajhi AA
    • Issue date: 2009 Mar
    • Targeting CD4 testing to a clinical subgroup of patients could limit unnecessary CD4 measurements, premature antiretroviral treatment and costs in Thyolo District, Malawi.
    • Authors: Zachariah R, Teck R, Ascurra O, Humblet P, Harries AD
    • Issue date: 2006 Jan
    • Characteristics of HIV-infected tuberculosis patients in Thailand.
    • Authors: Mankatittham W, Likanonsakul S, Thawornwan U, Kongsanan P, Kittikraisak W, Burapat C, Akksilp S, Sattayawuthipong W, Srinak C, Nateniyom S, Tasaneeyapan T, Varma JK
    • Issue date: 2009 Jan
    • Should absolute lymphocyte count be used as a surrogate marker for CD4+ count in patients with HIV/AIDS?
    • Authors: Jibrin YB, Yusuph H, Garbati MA, Gashau W, Abja UM
    • Issue date: 2006 Mar
    • CD4 cell count recovery in HIV/TB co-infected patients versus TB uninfected HIV patients.
    • Authors: Wanchu A, Kuttiatt VS, Sharma A, Singh S, Varma S
    • Issue date: 2010 Oct-Dec
    DSpace software (copyright © 2002 - 2021)  DuraSpace
    Quick Guide | Contact Us
    Open Repository is a service operated by 
    Atmire NV
     

    Export search results

    The export option will allow you to export the current search results of the entered query to a file. Different formats are available for download. To export the items, click on the button corresponding with the preferred download format.

    By default, clicking on the export buttons will result in a download of the allowed maximum amount of items.

    To select a subset of the search results, click "Selective Export" button and make a selection of the items you want to export. The amount of items that can be exported at once is similarly restricted as the full export.

    After making a selection, click one of the export format buttons. The amount of items that will be exported is indicated in the bubble next to export format.