Browsing MSF Research Protocols by Authors
Case-study: A retrospective assessment of transmission of Ebola virus disease (EVD) through a rural Sierra Leonean community and the impact on mortality and health seeking behaviours.Duncombe, Jennifer; Caleo, Grazia; Mills, Clair; Passmore, Charlotte; Kremer, Ronald; Lokuge, Kamalini; Greig, Jane; Lamin, Manjo; MSF-OCA (2018-07)OBJECTIVES 2.1. PRIMARY OBJECTIVES To provide a comprehensive description of mortality and transmission of EVD and the community response to EVD in one rural Sierra Leonean community in Kailahun District throughout the course of an outbreak. 2.2. SECONDARY OBJECTIVES 1. Describe the transmission and associated morbidity and mortality of EVD within the village throughout the course of the outbreak, with particular attention to the period prior to the MSF Ebola Management Centre (EMC) opening in Kailahun district (May-June 2014) and the period during which it was receiving cases from the village under study (July-November 2014). 2. Estimate overall and cause-specific mortality (EVD and non-EVD) in under-5 and 5 and older populations within the study village 3. Estimate the secondary cases due to Ebola in quarantined and non-quarantined households. 4. Document the broader impact of the Ebola virus outbreak on health-seeking behaviours and disease outcomes in general, including changes in access to healthcare, illness beliefs and perceptions of healthcare providers. 5. Determine level and factors associated with access and uptake of MSF EMC services within affected households.
Retrospective population-based mortality survey in an urban and rural area of Sierra Leone, 2015Caleo, Grazia; Kardamanidis, Katina; Broeder, Rob; Belava, Jaroslava; Kremer, Ronald; Lokuge, Kamalini; Greig, Jane; Turay; Saffa, Gbessay; MSF-OCA (2018-07)2. Objectives 2.1. Primary objectives The Primary objective of the survey is to: Estimate mortality in a sample of the population in the urban and rural area of Bo District from the approximate start of the Ebola outbreak in Sierra Leone (mid May 2014) until the day of the survey. 2.2. Secondary objectives Estimate overall and cause-specific mortality (EVD and non-EVD) in children under the age of 5 years, and the population aged 5 years and older within the study area, with particular attention to the period prior to the MSF Ebola Management Centre (EMC) opening in Bo district (19 September 2014) and the period during which it was receiving cases from the district (last confirmed case exited 26 January 2015); Estimate overall and cause-specific mortality (EVD and non-EVD) in quarantined and non-quarantined households; and contact-traced and non-contact-traced households; Describe health seeking behaviour in terms of whether health care was sought, where health care was sought and whether access to health care was possible.