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    Apr 19, 2021
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    Time to initiation of antiretroviral therapy among patients with HIV-associated tuberculosis in Cape Town, South Africa

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    Lawn Time to Initiation of ...
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    Authors
    Lawn, Stephen D
    Campbell, Lucy
    Kaplan, Richard
    Boulle, Andrew
    Cornell, Morna
    Kerschberger, Bernhard
    Morrow, Carl
    Little, Francesca
    Egger, Matthias
    Wood, Robin
    Affiliation
    The Desmond Tutu HIV Centre, Institute for Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; Department of Clinical Research, Faculty of Infectious and Tropical Diseases, London School of Hygiene & Tropical Medicine, London, UK; Department of Statistical Sciences, Faculty of Science, University of Cape Town, South Africa; School of Public Health and Family Medicine, Faculty of Health Sciences, University of Cape Town, Cape Town, South Africa; Medecins Sans Frontieres, Cape Town, South Africa; Division of International and Environmental Health, Institute of Social and Preventive Medicine (ISPM), University of Bern, Switzerland
    Issue Date
    2011-06-01
    
    Metadata
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    Journal
    Journal of Acquired Immune Deficiency Syndromes (JAIDS)
    Abstract
    We studied the time interval between starting tuberculosis treatment and commencing antiretroviral treatment (ART) in HIV-infected patients (n = 1433; median CD4 count 71 cells per microliter, interquartile range: 32-132) attending 3 South African township ART services between 2002 and 2008. The overall median delay was 2.66 months (interquartile range: 1.58-4.17). In adjusted analyses, delays varied between treatment sites but were shorter for patients with lower CD4 counts and those treated in more recent calendar years. During the most recent period (2007-2008), 4.7%, 19.7%, and 51.1% of patients started ART within 2, 4, and 8 weeks of tuberculosis treatment, respectively. Operational barriers must be tackled to permit further acceleration of ART initiation as recommended by 2010 WHO ART guidelines.
    Publisher
    Lippincott Williams & Wilkins
    URI
    http://hdl.handle.net/10144/255367
    DOI
    10.1097/QAI.0b013e3182199ee9
    PubMed ID
    21436714
    Additional Links
    http://journals.lww.com/jaids/Abstract/2011/06010/Time_to_Initiation_of_Antiretroviral_Therapy_Among.7.aspx
    Type
    Article
    Language
    en
    Description
    Article approval pending
    ISSN
    1944-7884
    ae974a485f413a2113503eed53cd6c53
    10.1097/QAI.0b013e3182199ee9
    Scopus Count
    Collections
    HIV/AIDS

    entitlement

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