Use of a Cholera Rapid Diagnostic Test during a Mass Vaccination Campaign in Response to an Epidemic in Guinea, 2012
Authors
Martinez-Pino, IsabelLuquero, Francisco J
Sakoba, Kéïta
Sylla, Souleymane
Haile, Melatwork
Grais, Rebecca F
Ciglenecki, Iza
Quilici, Marie-Laure
Page, Anne-Laure
Affiliation
European Programme for Intervention Epidemiology Training (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden ; Epicentre, Paris, France.Issue Date
2013-08-15
Metadata
Show full item recordJournal
PLoS Neglected Tropical DiseasesAbstract
During the 2012 cholera outbreak in the Republic of Guinea, the Ministry of Health, supported by Médecins Sans Frontières - Operational Center Geneva, used the oral cholera vaccine Shanchol as a part of the emergency response. The rapid diagnostic test (RDT) Crystal VC, widely used during outbreaks, detects lipopolysaccharide antigens of Vibrio cholerae O1 and O139, both included in Shanchol. In the context of reactive use of a whole-cell cholera vaccine in a region where cholera cases have been reported, it is essential to know what proportion of vaccinated individuals would be reactive to the RDT and for how long after vaccination.Publisher
Public Library of SciencePubMed ID
23967359Language
enISSN
1935-2735ae974a485f413a2113503eed53cd6c53
10.1371/journal.pntd.0002366